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Bus Knoxville, TN to Greenville, SC: Trip Overview
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Based on 87162 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at US$56
Knoxville to Greenville Bus
With Busbud, comparing and booking tickets for a bus from Knoxville to Greenville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make it our job to connect you with the most dependable bus companies that cover bus service from Knoxville to Greenville.
Whether it is cheap bus tickets or more luxurious buses going to Greenville from Knoxville, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Knoxville and Greenville?
Frequently asked questions on the trip Knoxville, TN - Greenville, SC
How far is Greenville from Knoxville by coach?
The distance between Knoxville and Greenville by coach is approximately 115 miles (186 km).
Is there a way to reach Greenville from Knoxville without a car?
You can travel to Greenville from Knoxville by coach, which provides a smooth ride and an affordable and convenient trip. Depending on your preferences, carpooling can also be considered as an option.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Greenville, SC as early as possible.
You can expect to pay from US$49 to US$97 for a bus ticket from Knoxville, TN to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at US$49, which is on 2025-08-08.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Knoxville to Greenville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Knoxville to Greenville.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Knoxville to Greenville.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Knoxville to Greenville.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
Top travelled bus routes
Why choose Busbud?
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Popular Buses Connecting Knoxville
Buses Leaving from Knoxville
- Bus from Knoxville to Charlotte
- Coach Knoxville - Marathon
- Bus Knoxville - Lexington
- Knoxville - Orlando
- Bus from Knoxville to Chicago
- Coach Knoxville - Lubbock
- Bus Knoxville - Nashville
- Knoxville - Miami
- Bus from Knoxville to New York City
- Coach Knoxville - Myrtle Beach
- Bus Knoxville - Greenville
- Knoxville - San Diego
- Bus from Knoxville to Portland
- Coach Knoxville - Jackson
- Bus Knoxville - Memphis
Buses Going to Knoxville
- Bus from Nashville to Knoxville
- Coach Memphis - Knoxville
- Bus Charlotte - Knoxville
- Chicago - Knoxville
- Bus from Tampa to Knoxville
- Coach Richmond - Knoxville
- Bus Greeneville - Knoxville
- Spartanburg - Knoxville
- Bus from Frederick to Knoxville
- Coach Washington - Knoxville
- Bus Columbus - Knoxville
- Atlanta - Knoxville
- Bus from Bloomington to Knoxville
- Coach El Paso - Knoxville
- Bus Murfreesboro - Knoxville
Popular Buses Connecting Greenville
Buses Leaving from Greenville
- Bus from Greenville to Charleston
- Coach Greenville - Charleston
- Bus Greenville - Spartanburg
- Greenville - Greensboro
- Bus from Greenville to Miami
- Coach Greenville - Chicago
- Bus Greenville - Columbus
- Greenville - Oklahoma City
- Bus from Greenville to New York City
- Coach Greenville - San Antonio
- Bus Greenville - Atlanta
- Greenville - Charlotte
- Bus from Greenville to Anderson
- Coach Greenville - Lima
Buses Going to Greenville
- Bus from Atlanta to Greenville
- Coach Burlington - Greenville
- Bus Nashville - Greenville
- Savannah - Greenville
- Bus from Knoxville to Greenville
- Coach Charlotte - Greenville
- Bus Myrtle Beach - Greenville
- Memphis - Greenville
- Bus from Lima to Greenville
- Coach Spartanburg - Greenville
- Bus Dublin - Greenville
- Pittsburgh - Greenville
- Bus from Durham to Greenville
- Coach Miami - Greenville
Popular routes in this country
- Bus from Austin to Houston
- Coach New York City - Burlington
- Bus Niagara Falls - New York City
- Dallas - Austin
- Bus from Houston to Austin
- Coach Austin - Dallas
- Bus Atlanta - Savannah
- Philadelphia - New York City
- Bus from Tallahassee to Panama City
- Coach New York City - Los Angeles
- Bus Baton Rouge - New Orleans
Popular airport transfers
- Travel in United States
- Bus to Knoxville, TN
- Bus to Greenville, SC
- Knoxville, TN to Greenville, SC Buses