Find coaches from Greenville, SC to Knoxville, TN

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Fri8 Aug
from US$48
Sat9 Aug
from US$45
Sun10 Aug
from US$76
Mon11 Aug
Tue12 Aug
Wed13 Aug
Thu14 Aug
Fri15 Aug

Cheap buses leaving Saturday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: 9 August at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: 9 August at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Greenville, SC to Knoxville, TN: Trip Overview

Average ticket priceUS$75
Average bus trip duration7h 5m
Number of daily buses1
Earliest bus departure14:45
Distance120 miles

Greenville to Knoxville Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Greenville to Knoxville.

Bus service from Greenville to Knoxville will be provided by the most trusted bus companies.

Discover how much the bus trip from Greenville to Knoxville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Greenville, SC - Knoxville, TN

  1. What's the distance between Greenville and Knoxville by coach?

    The journey from Greenville to Knoxville by coach covers an approximate distance of 115 miles (186 km).

  2. How can I get from Greenville to Knoxville without driving?

    You can reach Knoxville from Greenville by coach, as there are regular services between the two locations. Depending on your preferences, carpooling can also be considered as an option.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/08
US$49
05/08
No data
Today
US$42
07/08
US$97
08/08
US$41
09/08
US$37
10/08
US$68
11/08
No data
busbud logoThe cheapest trip from Greenville, SC to Knoxville, TN was searched and found on 9 Aug 2025 with a price of US$37

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Knoxville, TN as early as possible.

You can expect to pay from US$37 to US$97 for a bus ticket from Greenville, SC to Knoxville, TN based on the last 2 days. You can expect to find the cheapest price for the trip at US$37, which is on 2025-08-09.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Greenville to Knoxville but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Greenville to Knoxville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Greenville to Knoxville will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Make a music playlist for your bus ride from Greenville to Knoxville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Greenville, SC by bus?

Bus from Greenville, SC to Knoxville, TN

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