Find coaches from Detroit, MI to Knoxville, TN

Find affordable coach tickets from Detroit, MI to Knoxville, TN with flexible options. Book your journey now

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Today11 Aug
Tomorrow12 Aug
from US$78
Wed13 Aug
Thu14 Aug
from US$78
Fri15 Aug
from US$78
Sat16 Aug
from US$78
Sun17 Aug
from US$72
Mon18 Aug

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: 12 August at
    Departure city: Detroit
    Departure location: Detroit Bus Station
    Arrival time: 12 August at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 12 August at
    Departure city: Detroit
    Departure location: Detroit Bus Station
    Arrival time: 13 August at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 12 August at
    Departure city: Detroit
    Departure location: Detroit Bus Station
    Arrival time: 13 August at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 12 August at
    Departure city: Detroit
    Departure location: Detroit Bus Station
    Arrival time: 13 August at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Detroit, MI to Knoxville, TN: Trip Overview

Average ticket priceUS$100
Average bus trip duration21h 10m
Number of daily buses4
Earliest bus departure06:40
Distance439 miles
Latest bus departure23:25

Detroit to Knoxville Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Detroit to Knoxville.

We make it our job to connect you with the most dependable bus companies that cover bus service from Detroit to Knoxville.

From cheap bus tickets to more luxurious buses travelling from Detroit to Knoxville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Detroit, MI - Knoxville, TN

  1. What's the distance between Detroit and Knoxville by coach?

    The journey from Detroit to Knoxville by coach covers an approximate distance of 443 miles (714 km).

  2. How can I travel from Detroit to Knoxville avoiding air travel?

    To travel from Detroit to Knoxville without flying, you can take the coaches. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/08
US$177
10/08
US$66
Today
US$75
12/08
US$70
13/08
US$75
14/08
US$70
15/08
US$70
16/08
US$70
busbud logoThe cheapest trip from Detroit, MI to Knoxville, TN was searched and found on 10 Aug 2025 with a price of US$66

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to Knoxville, TN as early as possible.

You can expect to pay from US$66 to US$224 for a bus ticket from Detroit, MI to Knoxville, TN based on the last 2 days. You can expect to find the cheapest price for the trip at US$70, which is on 2025-08-12.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Detroit to Knoxville but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Detroit to Knoxville.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Detroit to Knoxville that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Detroit to Knoxville while indulging in miles on end of beautiful scenic views.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Detroit, MI by bus?

Bus from Detroit, MI to Knoxville, TN

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Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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