Find coaches from Greenville (SC) to Gainesville (FL)

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Compare 2 ways to travel from Greenville to Gainesville

Bus
Average priceUS$49 - US$263Average duration12h 10m
14kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average priceUS$159 - US$175Average duration1d 6h
52kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Greenville to Gainesville

Among the sustainable travel choices, the bus stands out as a good way to reach Gainesville. The journey takes about 12 hours 10 minutes and with fares starting at just US$49, it presents an excellent value for a comfortable ride.

6bus per day
12h 10mAverage duration
US$49Cheapest ticket
14kgCO₂ emissions

Bus Greenville to Gainesville: Trip Overview

Average ticket priceUS$90
Average bus trip duration12h 10m
Number of daily buses6
Earliest bus departure10:55
Distance353 miles
Latest bus departure22:00

Greenville to Gainesville Bus

With Busbud, comparing and booking tickets for a bus from Greenville to Gainesville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Greenville to Gainesville from the most reliable bus companies operating this trip.

Discover how much the bus trip from Greenville to Gainesville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Greenville (SC) - Gainesville (FL)

  1. How much is the cheapest coach ticket from Greenville to Gainesville?

    The prices typically range from US$49 to US$263 on this trip, with the average ticket costing US$90. The cost of tickets can fluctuate based on factors like the time of day, the company, and the class you choose. Compare the prices and amenities offered by each company on Busbud and find the best deals and offers.

  2. How long does it take to travel from Greenville to Gainesville by bus?

    The coach journey between Greenville and Gainesville lasts about 12h 10m. If you're looking for the fastest trip, you can get there in just about 9h 15m. However, please keep in mind that your specific travel time may vary due to the prevailing traffic conditions along the route.

  3. When is the first coach from Greenville to Gainesville?

    The first coach to Gainesville from Greenville departs at 10:55. Times and services may vary during weekends and holidays.

  4. How far is Gainesville from Greenville by coach?

    The journey from Greenville to Gainesville by coach covers an approximate distance of 359 miles (579 km).

  5. Is there a way to reach Gainesville from Greenville without flying?

    You can choose the coach to travel this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
28/05
US$115
29/05
No data
Today
No data
31/05
No data
01/06
No data
02/06
US$54
03/06
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04/06
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busbud logoThe cheapest trip from Greenville to Gainesville was searched and found on 2 Jun 2025 with a price of US$54

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville to Gainesville as early as possible.

You can expect to pay from US$54 to US$250 for a bus ticket from Greenville to Gainesville based on the last 2 days. You can expect to find the cheapest price for the trip at US$54, which is on 2025-06-02.

Usually Expreso will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Greenville to Gainesville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Greenville to Gainesville, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Greenville to Gainesville will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Greenville to Gainesville while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

What's the cheapest way to go from Greenville to Gainesville?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Greenville by bus?

Bus from Greenville to Gainesville

You can also go to Gainesville by train

Train from Greenville to Gainesville

Why choose Busbud?

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Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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