Find coaches from Philadelphia, PA to Greenville, SC

Find affordable coach tickets from Philadelphia, PA to Greenville, SC with flexible options. Book your journey now

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Today11 Aug
Tomorrow12 Aug
from US$89
Wed13 Aug
from US$89
Thu14 Aug
from US$100
Fri15 Aug
from US$90
Sat16 Aug
Sun17 Aug
from US$87
Mon18 Aug

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 12 August at
    Departure city: Philadelphia
    Departure location: 199 Spring Garden St.
    Arrival time: 13 August at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 12 August at
    Departure city: Philadelphia
    Departure location: Philadelphia, 199 Spring Garden St
    Arrival time: 13 August at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 12 August at
    Departure city: Philadelphia
    Departure location: 199 Spring Garden St.
    Arrival time: 13 August at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: 12 August at
    Departure city: Philadelphia
    Departure location: Philadelphia, 199 Spring Garden St
    Arrival time: 12 August at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 12 August at
    Departure city: Philadelphia
    Departure location: Schuylkill & Walnut
    Arrival time: 13 August at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to travel from Philadelphia to Greenville

Bus
Average priceUS$65 - US$213Average duration18h 35m
21kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average priceUS$100 - US$325Average duration13h 46m
78kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Philadelphia to Greenville

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 18 hours 35 minutes and with fares starting at just US$65, it presents an excellent value for a comfortable ride.

18bus per day
18h 35mAverage duration
US$65Cheapest ticket
21kgCO₂ emissions

Bus Philadelphia, PA to Greenville, SC: Trip Overview

Average ticket priceUS$99
Average bus trip duration18h 35m
Number of daily buses18
Earliest bus departure01:50
Distance529 miles
Latest bus departure23:15

Philadelphia to Greenville Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Philadelphia to Greenville.

We make it our job to connect you with the most dependable bus companies that cover bus service from Philadelphia to Greenville.

Discover how much the bus trip from Philadelphia to Greenville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Philadelphia, PA - Greenville, SC

  1. What's the distance between Philadelphia and Greenville by coach?

    The distance between Philadelphia and Greenville by coach is approximately 530 miles (855 km).

  2. What is the best way to go from Philadelphia to Greenville without flying?

    You have the option to select the coach for your journey on this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/08
US$86
10/08
US$127
Today
US$88
12/08
US$81
13/08
US$81
14/08
US$93
15/08
US$82
16/08
US$79
busbud logoThe cheapest trip from Philadelphia, PA to Greenville, SC was searched and found on 16 Aug 2025 with a price of US$79

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to Greenville, SC as early as possible.

You can expect to pay from US$79 to US$171 for a bus ticket from Philadelphia, PA to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at US$79, which is on 2025-08-16.

Usually Greyhound Lines, Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Philadelphia to Greenville but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Philadelphia to Greenville.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Philadelphia to Greenville will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Make a music playlist for your bus ride from Philadelphia to Greenville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

What's the cheapest way to go from Philadelphia, PA to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Philadelphia, PA by bus?

Bus from Philadelphia, PA to Greenville, SC

You can also go to Greenville, SC by train

Train from Philadelphia, PA to Greenville, SC

Why choose Busbud?

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