Bus Tickets from Greenville (SC) to Gainesville (FL)

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Compare 2 ways to go from Greenville to Gainesville

Bus
Average PriceUS$49 - US$263Average Duration12h 10m
14kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$159 - US$175Average Duration1d 6h
52kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Greenville to Gainesville

Among the sustainable travel choices, the bus stands out as a good way to reach Gainesville. The journey takes about 12 hours 10 minutes, and with fares starting at just US$49, it presents an excellent value for a comfortable ride.

6bus per day
12h 10mAverage Duration
US$49Cheapest ticket
14kgCO₂ emissions

Bus Greenville to Gainesville: Trip Overview

Average Ticket PriceUS$90
Average Bus Trip Duration12h 10m
Number of daily buses6
Earliest bus departure10:55am
Distance569 km
Latest bus departure10:00pm

Greenville to Gainesville Bus

With Busbud, comparing and booking tickets for a bus from Greenville to Gainesville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Greenville to Gainesville from the most reliable bus companies operating this trip.

Discover how much the bus trip from Greenville to Gainesville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Greenville (SC) - Gainesville (FL)

  1. How long is the trip from Greenville to Gainesville by bus?

    The trip from Greenville to Gainesville will take on average 12h 10m. The fastest bus on this trip will get to Gainesville in 9h 15m

  2. What is the travel distance from Greenville to Gainesville?

    It's about 579 km (359 miles) from Greenville to Gainesville.

  3. What are the departure and arrival locations for buses traveling from Greenville to Gainesville?

    Buses departing from Guadalajara Supermarket Bus Stop in Greenville will take you to Rosa Parks Station in Gainesville.

  4. What is the cheapest way to travel from Greenville to Gainesville?

    Taking the bus is the cheapest option to travel from Greenville to Gainesville. The ticket price for this bus starts at US$49, making this your best choice for this trip.

  5. How much does the bus ticket cost from Greenville to Gainesville?

    You can expect to pay around US$90 for the bus ride from Greenville to Gainesville.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-28
US$115
05-29
No data
Today
No data
05-31
No data
06-01
No data
06-02
US$54
06-03
No data
06-04
No data
busbud logoThe cheapest trip from Greenville to Gainesville was searched and found on Jun 2, 2025 with a price of US$54

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville to Gainesville, as early as possible.

You can expect to pay from US$54 to US$250 for a bus ticket from Greenville to Gainesville based on the last 2 days. You can expect to find the cheapest price for the trip at US$54 which is on 2025-06-02.

Usually Expreso will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Greenville to Gainesville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Greenville to Gainesville, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Greenville to Gainesville will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Greenville to Gainesville while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

What's the cheapest way to go from Greenville to Gainesville?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Greenville by bus?

Bus from Greenville to Gainesville

You can also go to Gainesville by train

Train from Greenville to Gainesville

Why choose Busbud?

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