Next departures for Syracuse to Charlotte on November 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Syracuse (Regional Transportation Center)
Charlotte Bus Station
Cheapest
FlixBus + Greyhound Lines, Inc.
Bus
Syracuse (Regional Transportation Center)
Charlotte Bus Station
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Syracuse (Regional Transportation Center)
Charlotte Bus Station
No tags
Bus
Syracuse (Regional Transportation Center)
Charlotte Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Syracuse (Regional Transportation Center)
Charlotte Bus Station
No tags
Next departures for Syracuse to Charlotte on November 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Syracuse (Regional Transportation Center)
Charlotte Bus Station
CheapestFastest
Bus
Syracuse (Regional Transportation Center)
Charlotte Bus Station
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Syracuse (Regional Transportation Center)
Charlotte Bus Station
No tags
Bus
Syracuse (Regional Transportation Center)
Charlotte Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Syracuse (Regional Transportation Center)
Charlotte Bus Station
No tags
Next departures for Syracuse to Charlotte on November 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Syracuse (Regional Transportation Center)
Charlotte Bus Station
Cheapest
FlixBus + Greyhound Lines, Inc.
Bus
Syracuse (Regional Transportation Center)
Charlotte Bus Station
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Syracuse (Regional Transportation Center)
Charlotte Bus Station
No tags
Bus
Syracuse (Regional Transportation Center)
Charlotte Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Syracuse (Regional Transportation Center)
Charlotte Bus Station
No tags
Last refresh of the prices: Last Thursday at 1:19 AM EST.
Compare 2 ways to go from Syracuse to Charlotte
We recommend taking the train
Among the sustainable travel choices, the train stands out as a good way to reach Charlotte. The journey takes about 19 hours 24 minutes, and with fares starting at just $264, it presents an excellent value for a comfortable ride.
Based on 11422 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the WiFi. FlixBus ticket prices on this trip start at $135
Based on 87393 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $130
Based on 4412 reviews, the company was rated 3.9 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the WiFi. New York Trailways ticket prices on this trip start at $508
Based on 1126 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the ticket access and the cleanliness but often complained with the WiFi. Adirondack Trailways ticket prices on this trip start at $508
Frequently asked questions about travelling from Syracuse, US to Charlotte, NC by bus
What is the travel distance from Syracuse to Charlotte?
The distance between Syracuse and Charlotte is approximately 960 km (596 miles).
What are the departure and arrival locations for buses traveling from Syracuse to Charlotte?
Buses departing from Regional Transportation Center in Syracuse will take you to Tornado & El Expreso Bus Company in Charlotte.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11-22
$249
11-23
$266
Today
$194
11-25
$443
11-26
$182
11-27
$192
11-28
$199
11-29
$320
The cheapest trip from Syracuse, US to Charlotte, NC was searched and found on Nov 26, 2025 with a price of $182
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Charlotte, NC, as early as possible.
You can expect to pay from $182 to $443 for a bus ticket from Syracuse, US to Charlotte, NC based on the last 2 days. You can expect to find the cheapest price for the trip at $182 which is on 2025-11-26.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Syracuse, US to Charlotte, NC?
The bus is the cheapest travel choice for this destination
The cheapest trip from Syracuse, US to Charlotte, NC was searched and found on Nov 26, 2025 with a price of $182
The bus is the cheapest travel choice for this destination
