Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Syracuse (Regional Transportation Center) | Charlotte (Freedom Dr) | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Syracuse (Regional Transportation Center) | Charlotte Bus Station | Fastest | ||||
 | Bus | Syracuse (Regional Transportation Center) | Charlotte Bus Station | No tags | ||||
 | Bus | Syracuse (Regional Transportation Center) | Charlotte Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Syracuse (Regional Transportation Center) | Charlotte Bus Station | No tags |
Last refresh of the prices: Last Sunday at 6:02 PM EDT.
Compare 2 ways to go from Syracuse to Charlotte
Among the sustainable travel choices, the Train stands out as a good way to reach Charlotte. The journey takes about 19 hours 24 minutes, and with fares starting at just $256, it presents an excellent value for a comfortable ride.
Where are the popular stops in Syracuse and Charlotte?
Stops in Syracuse
- A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208 - CBus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
- D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA - E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA - F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
Stops in Charlotte
- A
Tornado & El Expreso Bus Company
4705 N. Tryon S, Charlotte, NC, USA - C
Charlotte Greyhound Bus Station
601 W Trade St , Charlotte, NC 28202 - D
Agencia El Salvador Bus Stop
4335 N Tryon St, Charlotte, NC 28213 - E
4127 Glenwood Dr
4127 Glenwood Dr, Charlotte, NC 28208 (Exxon Gas Station)
Compare bus companies
Frequently asked questions about travelling from Syracuse, US to Charlotte, NC by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Syracuse to Charlotte?
The cheapest bus tickets from Syracuse to Charlotte start from $121. The average price for this route is around $187. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Syracuse to Charlotte?
The average bus travel time from Syracuse to Charlotte is 21h 45m, covering a distance of 961 km. The quickest bus can get you there in 18h 45m and is operated by New York Trailways.
Which bus companies service the Syracuse to Charlotte route?
Several major bus companies operate on this route with 9 buses available per day, including services from FlixBus, Greyhound, New York Trailways, Adirondack Trailways.
What are the earliest and latest departure times for the bus from Syracuse to Charlotte?
The earliest bus departs from Syracuse to Charlotte at 1:15am. And the latest bus departs at 9:00pm.
What are the CO₂ emissions for the bus trip from Syracuse to Charlotte?
A bus trip from Syracuse to Charlotte generates an estimated 24 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Syracuse to Charlotte?
According to Busbud customers, the highest-rated bus company on this route is Adirondack Trailways, with an average rating of 4.1 out of 5 stars based on 1150 reviews.
Which bus company has the best Wi-Fi from Syracuse to Charlotte?
Based on Busbud reviews, the bus company New York Trailways has the highest Wi-Fi rating with a score of 3.1.
Which bus company has the best on-time performance from Syracuse to Charlotte?
According to Busbud traveller reviews, the most punctual bus company on this route is Adirondack Trailways, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Syracuse to Charlotte?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Adirondack Trailways, with a cleanliness rating of 4.7 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Syracuse, US to Charlotte, NC was searched and found on Mar 13, 2026 with a price of $237To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Charlotte, NC, as early as possible.
You can expect to pay from $237 to $349 for a bus ticket from Syracuse, US to Charlotte, NC based on the last 2 days. You can expect to find the cheapest price for the trip at $287 which is on 2026-03-15.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Syracuse, US to Charlotte, NC?
The Bus is the cheapest travel choice for this destination
