Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Syracuse (Regional Transportation Center) | Charlotte Bus Station | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Syracuse (Regional Transportation Center) | Charlotte Bus Station | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Syracuse (Regional Transportation Center) | Charlotte Bus Station | No tags | ||||
 | Bus | Syracuse (Regional Transportation Center) | Charlotte Bus Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Syracuse (Regional Transportation Center) | Charlotte Bus Station | No tags |
Last refresh of the prices: Last Thursday at 01:19 EST.
Compare 2 ways to travel from Syracuse to Charlotte
Among the sustainable travel choices, the train stands out as a good way to reach Charlotte. The journey takes about 19 hours 24 minutes and with fares starting at just £143, it presents an excellent value for a comfortable ride.
Where are the popular stops in Syracuse and Charlotte?
Stops in Syracuse
- A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208 - CBus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
- D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA - E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA - F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
Stops in Charlotte
- A
Tornado & El Expreso Bus Company
4705 N. Tryon S, Charlotte, NC, USA - C
Charlotte Greyhound Bus Station
601 W Trade St , Charlotte, NC 28202 - D
Agencia El Salvador Bus Stop
4335 N Tryon St, Charlotte, NC 28213 - E
4127 Glenwood Dr
4127 Glenwood Dr, Charlotte, NC 28208 (Exxon Gas Station)
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Frequently asked questions about travelling by bus from Syracuse, US to Charlotte, NC
How far is Charlotte from Syracuse by coach?
The journey from Syracuse to Charlotte by coach covers an approximate distance of 596 miles (960 km).
Is there a way to reach Charlotte from Syracuse without flying?
To travel from Syracuse to Charlotte without flying, you can take the coaches. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Syracuse, US to Charlotte, NC was searched and found on 26 Nov 2025 with a price of £99To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Charlotte, NC as early as possible.
You can expect to pay from £99 to £240 for a bus ticket from Syracuse, US to Charlotte, NC based on the last 2 days. You can expect to find the cheapest price for the trip at £99, which is on 2025-11-26.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Syracuse, US to Charlotte, NC?
The bus is the cheapest travel choice for this destination
