Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Syracuse (Regional Transportation Center) | Charlotte Bus Station | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Syracuse (Regional Transportation Center) | Charlotte Bus Station | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Syracuse (Regional Transportation Center) | Charlotte Bus Station | No tags | ||||
 | Bus | Syracuse (Regional Transportation Center) | Charlotte Bus Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Syracuse (Regional Transportation Center) | Charlotte Bus Station | No tags |
Last refresh of the prices: Last Thursday at 1:19 AM EST.
Compare 2 ways to travel from Syracuse to Charlotte
Among the sustainable travel choices, the train stands out as a good way to reach Charlotte. The journey takes about 19 hours 24 minutes and with fares starting at just R 3 237, it presents an excellent value for a comfortable ride.
Where are the popular stops in Syracuse and Charlotte?
Stops in Syracuse
- A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208 - B
Syracuse Airport
- CBus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
- D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA - E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA - F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
Stops in Charlotte
- A
Tornado & El Expreso Bus Company
4705 N. Tryon S, Charlotte, NC, USA - C
Charlotte Greyhound Bus Station
601 W Trade St , Charlotte, NC 28202 - D
Agencia El Salvador Bus Stop
4335 N Tryon St, Charlotte, NC 28213 - E
4127 Glenwood Dr
4127 Glenwood Dr, Charlotte, NC 28208 (Exxon Gas Station)
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Frequently asked questions about travelling from Syracuse, US to Charlotte, NC by bus
How much does a bus ticket from Syracuse to Charlotte cost?
The bus ticket price from Syracuse to Charlotte starts at R 1 592. The best way to find cheap bus tickets from Syracuse to Charlotte is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Syracuse to Charlotte?
The average travel time between Syracuse and Charlotte is around 21h 20m, although the fastest bus will take about 18h 25m. This is the time it takes to travel the 960 km that separates the two cities.
How many daily bus connections are there between Syracuse and Charlotte?
The number of buses from Syracuse to Charlotte can differ depending on the day of the week. On average, there are 9 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Syracuse to Charlotte by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Syracuse to Charlotte?
When taking the bus from Syracuse to Charlotte, you can travel comfortably and safely with FlixBus, Greyhound, New York Trailways.
What are the departure and arrival stations when taking the bus from Syracuse to Charlotte?
Buses travelling between Syracuse and Charlotte leave from Regional Transportation Center or Syracuse Airport and arrive at Tornado & El Expreso Bus Company, Charlotte Douglas International Airport, Charlotte Greyhound Bus Station.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Syracuse, US to Charlotte, NC was searched and found on 26 Nov 2025 with a price of R 2 227To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Charlotte, NC as early as possible.
You can expect to pay from R 2 227 to R 5 431 for a bus ticket from Syracuse, US to Charlotte, NC based on the last 2 days. You can expect to find the cheapest price for the trip at R 2 227, which is on 2025-11-26.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Syracuse, US to Charlotte, NC?
The bus is the cheapest travel choice for this destination
