Bus Tickets from Mexico City to Zacatecas

Find affordable bus tickets from Mexico City to Zacatecas with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayAug 7
from US$83
TomorrowAug 8
from US$68
SatAug 9
from US$68
SunAug 10
from US$68
MonAug 11
from US$68
TueAug 12
from US$68
WedAug 13
from US$68
ThuAug 14
from US$68

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: August 8 at
    Departure city: Mexico City
    Departure location: Mexico D.F. Norte - 4907 EJE Central Lazaro Cardenas
    Arrival time: August 8 at
    Destination city: Zacatecas
    Destination location: Tránsito Pesado - Lomas de las Isabelica
    Operated by: Valle del GuadianaValle del Guadiana
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: August 8 at
    Departure city: Mexico City
    Departure location: Mexico D.F. Norte - 4907 EJE Central Lazaro Cardenas
    Arrival time: August 9 at
    Destination city: Zacatecas
    Destination location: Tránsito Pesado - Lomas de las Isabelica
    Operated by: ChihuahuensesChihuahuenses
    Vehicle: BusDuration:
  • Departure time: August 8 at
    Departure city: Mexico City
    Departure location: Mexico D.F. Norte - 4907 EJE Central Lazaro Cardenas
    Arrival time: August 8 at
    Destination city: Zacatecas
    Destination location: Tránsito Pesado - Lomas de las Isabelica
    Operated by: ChihuahuensesChihuahuenses
    Vehicle: BusDuration:
  • Departure time: August 8 at
    Departure city: Mexico City
    Departure location: Mexico D.F. Norte - 4907 EJE Central Lazaro Cardenas
    Arrival time: August 9 at
    Destination city: Zacatecas
    Destination location: Tránsito Pesado - Lomas de las Isabelica
    Operated by: FuturaFutura
    Vehicle: BusDuration:
  • Departure time: August 8 at
    Departure city: Mexico City
    Departure location: Mexico City Cerro de Jesús
    Arrival time: August 9 at
    Destination city: Zacatecas
    Destination location: Central de Autobuses de Zacatecas - Grupo Senda y Omnibus
    Operated by: TuristarTuristar
    Vehicle: BusDuration:

Last refresh of the prices: Today at 12:31 AM CST.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 4 ways to go from Mexico City to Zacatecas

Bus
Average PriceUS$67 - US$175Average Duration9h 55m
13kg CO₂e5 out of 5 stars
Most eco-friendly
Van
Average PriceUS$68 - US$68Average Duration12h 35m
16kg CO₂e4 out of 5 stars
Shuttle
Average PriceUS$71 - US$71Average Duration11h 5m
16kg CO₂e4 out of 5 stars
Carpool
Average PriceUS$27 - US$46Average Duration7h 50m
21kg CO₂e4 out of 5 stars
CheapestFastest
busbud logoBusbud recommends carpooling from Mexico City to Zacatecas

Among the sustainable travel choices, the carpool stands out as a good way to reach Zacatecas. The journey takes about 7 hours 50 minutes, and with fares starting at just US$27, it presents an excellent value for a comfortable ride.

1carpool per day
7h 50mAverage Duration
US$27Cheapest ticket
21kgCO₂ emissions

Bus Mexico City to Zacatecas: Trip Overview

Average Ticket PriceUS$96
Average Bus Trip Duration9h 55m
Number of daily buses32
Earliest bus departure12:00am
Distance510 km
Latest bus departure11:59pm

Mexico City to Zacatecas Bus

Busbud helps you find a bus from Mexico City to Zacatecas. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Mexico City to Zacatecas will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Zacatecas from Mexico City, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Mexico City - Zacatecas

  1. How far is Mexico City from Zacatecas?

    Mexico City and Zacatecas are 516 km (320 miles) apart.

  2. What are the departure and arrival locations for buses traveling from Mexico City to Zacatecas?

    Buses departing from Sur in Mexico City will take you to Central de Autobuses de Zacatecas - Grupo Senda y Omnibus in Zacatecas.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-05
US$73
08-06
US$74
Today
US$59
08-08
US$59
08-09
US$59
08-10
US$59
08-11
US$59
08-12
US$59
busbud logoThe cheapest trip from Mexico City to Zacatecas was searched and found on Aug 7, 2025 with a price of US$59

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mexico City to Zacatecas, as early as possible.

You can expect to pay from US$59 to US$114 for a bus ticket from Mexico City to Zacatecas based on the last 2 days. You can expect to find the cheapest price for the trip at US$59 which is on 2025-08-08.

Usually TURS will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Mexico City and Zacatecas!

Much more than a mere vehicle taking you from Mexico City to Zacatecas, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Mexico City to Zacatecas.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Mexico City to Zacatecas.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Mexico City by bus?

Bus from Mexico City to Zacatecas

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Mexico City

Buses Leaving from Mexico City

Buses Going to Mexico City

Popular Buses Connecting Zacatecas

Buses Leaving from Zacatecas

Buses Going to Zacatecas