Bus Tickets from Knoxville, TN to Buffalo, NY

Previously seen trips

Next departures for Knoxville to Buffalo on October 3
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
Knoxville Bus Station
Niagara Frontier Transportation AuthorityNo tags
Greyhound
Knoxville Bus Station
Niagara Frontier Transportation AuthorityNo tags
FlixBus + Greyhound
Knoxville Bus Station
Buffalo (BUF) AirportNo tags
Greyhound
Knoxville Bus Station
Niagara Frontier Transportation AuthorityNo tags
FlixBus + Greyhound
Knoxville Bus Station
Buffalo (BUF) AirportNo tags

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Knoxville, TN to Buffalo, NY: Trip Overview

Average Ticket PriceUS$71
Average Bus Trip Duration1d 5h
Number of daily buses2
Earliest bus departure10:00pm
Distance888 km
Latest bus departure10:50pm

Knoxville to Buffalo Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Knoxville to Buffalo.

We make sure you can find a bus service from Knoxville to Buffalo from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Knoxville to Buffalo, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Knoxville, TN - Buffalo, NY

  1. How far is Knoxville from Buffalo?

    Knoxville and Buffalo are 885 km (549 miles) apart.

  2. What are the departure and arrival locations for buses traveling from Knoxville to Buffalo?

    Buses departing from 100 Kirkwood St in Knoxville will take you to Buffalo Airport in Buffalo.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-01
No data
10-02
US$70
Today
US$74
10-04
No data
10-05
No data
10-06
US$62
10-07
US$62
10-08
No data
busbud logoThe cheapest trip from Knoxville, TN to Buffalo, NY was searched and found on Oct 6, 2025 with a price of US$62

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Buffalo, NY, as early as possible.

You can expect to pay from US$62 to US$74 for a bus ticket from Knoxville, TN to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at US$62 which is on 2025-10-06.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Knoxville to Buffalo but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Knoxville to Buffalo, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Knoxville to Buffalo that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Knoxville to Buffalo, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Will you be returning to Knoxville, TN by bus?

Bus from Buffalo, NY to Knoxville, TN

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Knoxville

Buses Leaving from Knoxville

Buses Going to Knoxville

Popular Buses Connecting Buffalo

Buses Leaving from Buffalo

Buses Going to Buffalo