Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Niagara Frontier Transportation Authority | Charlotte Bus Station | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Niagara Frontier Transportation Authority | Charlotte Bus Station | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Niagara Frontier Transportation Authority | Charlotte Bus Station | No tags | ||||
| Bus | Buffalo (BUF) Airport | Charlotte Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Niagara Frontier Transportation Authority | Charlotte (Freedom Dr) | No tags |
Last refresh of the prices: Today at 10:03 AM EST.
Compare 2 ways to go from Buffalo to Charlotte
Among the sustainable travel choices, the train stands out as a good way to reach Charlotte. The journey takes about 21 hours 45 minutes, and with fares starting at just $268, it presents an excellent value for a comfortable ride.
Where are the popular stops in Buffalo and Charlotte?
Stops in Buffalo
- B185 Ellicott St, Buffalo, NY 14203, USA
- C75 Exchange St, Buffalo, NY 14203, USA
Stops in Charlotte
- A
Tornado & El Expreso Bus Company
4705 N. Tryon S, Charlotte, NC, USA - C
Charlotte Greyhound Bus Station
601 W Trade St , Charlotte, NC 28202 - D
Agencia El Salvador Bus Stop
4335 N Tryon St, Charlotte, NC 28213 - E
4127 Glenwood Dr
4127 Glenwood Dr, Charlotte, NC 28208 (Exxon Gas Station)
Compare bus companies
Frequently asked questions about travelling from Buffalo, NY to Charlotte, NC by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Buffalo to Charlotte?
The cheapest bus tickets from Buffalo to Charlotte start from $134. The average price for this route is around $218. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Buffalo to Charlotte?
The average bus travel time from Buffalo to Charlotte is 1d , covering a distance of 868 km. The quickest bus can get you there in 22h 40m and is operated by FlixBus.
Which bus companies service the Buffalo to Charlotte route?
What are the earliest and latest departure times for the bus from Buffalo to Charlotte?
The earliest bus departs from Buffalo to Charlotte at 12:55am. And the latest bus departs at 11:59pm.
What are the CO₂ emissions for the bus trip from Buffalo to Charlotte?
A bus trip from Buffalo to Charlotte generates an estimated 22 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Buffalo to Charlotte?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11380 reviews.
Which bus company has the best Wi-Fi from Buffalo to Charlotte?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Buffalo to Charlotte?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Buffalo to Charlotte?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Buffalo, NY to Charlotte, NC was searched and found on Dec 6, 2025 with a price of $155To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to Charlotte, NC, as early as possible.
You can expect to pay from $155 to $486 for a bus ticket from Buffalo, NY to Charlotte, NC based on the last 2 days. You can expect to find the cheapest price for the trip at $155 which is on 2025-12-06.
What's the cheapest way to go from Buffalo, NY to Charlotte, NC?
The bus is the cheapest travel choice for this destination
