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- This trip is recommended because it is the: Cheapest + Fastest
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Bus Iowa City to St. Louis: Trip Overview
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Iowa City to St. Louis Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Iowa City to St. Louis.
Bus service from Iowa City to St. Louis will be provided by the most trusted bus companies.
From cheap bus tickets to more luxurious buses travelling from Iowa City to St. Louis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Iowa City and St. Louis?
Frequently asked questions on the trip Iowa City - St. Louis
How far is Iowa City from St. Louis?
The distance covered from Iowa City to St. Louis is 357 km (221 miles).
What are the departure and arrival locations for buses traveling from Iowa City to St. Louis?
Buses traveling this route start their trip at Court Street Bus Station, in Iowa City, and end it at Gateway Station, in St. Louis.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Iowa City to St. Louis was searched and found on Aug 30, 2025 with a price of US$86To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Iowa City to St. Louis, as early as possible.
You can expect to pay from US$86 to US$118 for a bus ticket from Iowa City to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$86 which is on 2025-09-01.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Iowa City to St. Louis but it'll also be endearing to native speakers who will surely appreciate your effort.
Much more than a mere vehicle taking you from Iowa City to St. Louis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Iowa City to St. Louis that are otherwise impossible to come by with a plane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Iowa City to St. Louis.
Did you know?
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
Top travelled bus routes
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Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
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Popular Buses Connecting Iowa City
Buses Leaving from Iowa City
- Bus from Iowa City to Ottumwa
- Bus Iowa City - Chicago
- Iowa City - Des Moines
- Bus from Iowa City to Minneapolis
- Bus Iowa City - Kansas City
- Iowa City - Omaha
- Bus from Iowa City to Boston
- Bus Iowa City - Lafayette
- Iowa City - Champaign
- Bus from Iowa City to Peoria
- Bus Iowa City - Topeka
- Iowa City - Memphis
- Bus from Iowa City to Eugene
- Bus Iowa City - Fort Walton Beach
- Iowa City - Los Angeles
Buses Going to Iowa City
- Bus from Des Moines to Iowa City
- Bus Waterloo - Iowa City
- Chicago - Iowa City
- Bus from Cedar Rapids to Iowa City
- Bus Hudson - Iowa City
- St. Louis - Iowa City
- Bus from South Bend to Iowa City
- Bus Cincinnati - Iowa City
- Ann Arbor - Iowa City
- Bus from Eugene to Iowa City
- Bus Newark - Iowa City
- Wichita - Iowa City
- Bus from Seattle to Iowa City
- Bus Philadelphia - Iowa City
- Toledo - Iowa City
Popular Buses Connecting St. Louis
Buses Leaving from St. Louis
- Bus from St. Louis to New Orleans
- Bus St. Louis - Kansas City
- St. Louis - Kansas City
- Bus from St. Louis to Nashville
- Bus St. Louis - Buffalo
- St. Louis - Austin
- Bus from St. Louis to Indianapolis
- Bus St. Louis - Chicago
- St. Louis - Columbia
- Bus from St. Louis to Houston
- Bus St. Louis - Champaign
- St. Louis - Lawrence
- Bus from St. Louis to Murfreesboro
- Bus St. Louis - Rockford
- St. Louis - Natchitoches
Buses Going to St. Louis
- Bus from Manchester to St. Louis
- Bus Manchester - St. Louis
- New Orleans - St. Louis
- Bus from Atlanta to St. Louis
- Bus Indianapolis - St. Louis
- Omaha - St. Louis
- Bus from Chicago to St. Louis
- Bus Pasco - St. Louis
- Springfield - St. Louis
- Bus from Cheyenne to St. Louis
- Bus Columbia - St. Louis
- Lafayette - St. Louis
- Bus from Memphis to St. Louis
- Bus Miami - St. Louis
- Champaign - St. Louis
Popular routes in this country
- Bus from Washington to New York City
- Bus Boston - New York City
- New York City - Boston
- Bus from Buffalo to New York City
- Bus Philadelphia - New York City
- Niagara Falls - New York City
- Bus from Baltimore to New York City
- Bus Detroit - Chicago
- Albany - New York City
- Bus from Los Angeles to San Francisco
- Bus Baton Rouge - New Orleans
- Los Angeles - San Diego
- Bus from Miami to Orlando
- Bus Las Vegas - Los Angeles
- Atlanta - Savannah