Next departures to Charleston
One passenger / one way
- This trip is recommended because it is the: Cheapest + FastestDeparture time: August 5 atDeparture city: IndianapolisDeparture location: Greyhound Amtrak StationArrival time: August 7 atDestination city: CharlestonDestination location: Charleston StationOperated by: Amtrak
Vehicle: BusDuration: - Departure time: August 5 atDeparture city: IndianapolisDeparture location: Greyhound Amtrak StationArrival time: August 7 atDestination city: CharlestonDestination location: Charleston StationOperated by: AmtrakVehicle: BusDuration:
Last refresh of the prices: Today at 6:44 AM EDT.
Prices and availability are subject to change.
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Compare 2 ways to go from Indianapolis to Charleston
Busbud recommends taking the bus from Indianapolis to CharlestonAmong the sustainable travel choices, the bus stands out as a good way to reach Charleston. The journey takes about 22 hours, and with fares starting at just US$147, it presents an excellent value for a comfortable ride.
Bus Indianapolis to Charleston, SC, US: Trip Overview
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Indianapolis to Charleston Bus
Busbud helps you find a bus from Indianapolis to Charleston. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
Bus service from Indianapolis to Charleston will be provided by the most trusted bus companies.
From cheap bus tickets to more luxurious buses travelling from Indianapolis to Charleston, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Indianapolis and Charleston?
Frequently asked questions on the trip Indianapolis - Charleston, SC, US
What is the distance between Indianapolis and Charleston?
The distance covered from Indianapolis to Charleston is 957 km (594 miles).
What are the departure and arrival locations for buses traveling from Indianapolis to Charleston?
Buses traveling this route start their trip at Greyhound Amtrak Station, in Indianapolis, and end it at Charleston Bus Station, in Charleston.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Indianapolis to Charleston, SC, US was searched and found on Aug 5, 2025 with a price of US$562To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Charleston, SC, US, as early as possible.
You can expect to pay from US$562 to US$862 for a bus ticket from Indianapolis to Charleston, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$562 which is on 2025-08-05.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Indianapolis and Charleston!
Much more than a mere vehicle taking you from Indianapolis to Charleston, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Indianapolis to Charleston that are otherwise impossible to come by with a plane.
Make a music playlist for your bus ride from Indianapolis to Charleston, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
What's the cheapest way to go from Indianapolis to Charleston, SC, US?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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Popular Buses Connecting Indianapolis
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Popular Buses Connecting Charleston
Buses Leaving from Charleston
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Buses Going to Charleston
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Popular routes in this country
- Bus from Washington to New York City
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- Buffalo - New York City
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