Find coaches from Indianapolis to Charleston, SC, US

Compare 2 ways to travel from Indianapolis to Charleston

Bus
Average priceUS$147 - US$170Average duration22h
24kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average priceUS$234 - US$282Average duration1d 4h
86kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Indianapolis to Charleston

Among the sustainable travel choices, the bus stands out as a good way to reach Charleston. The journey takes about 22 hours and with fares starting at just US$147, it presents an excellent value for a comfortable ride.

1bus per day
22hAverage duration
US$147Cheapest ticket
24kgCO₂ emissions

Bus Indianapolis to Charleston, SC, US: Trip Overview

Average ticket priceUS$153
Average bus trip duration22h
Number of daily buses1
Earliest bus departure15:50
Distance585 miles
Latest bus departure23:30

Indianapolis to Charleston Bus

Busbud helps you find a bus from Indianapolis to Charleston. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Indianapolis to Charleston will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Indianapolis to Charleston, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Indianapolis - Charleston, SC, US

  1. How far is Charleston from Indianapolis by coach?

    The distance between Indianapolis and Charleston by coach is approximately 594 miles (957 km).

  2. What is the best way to go from Indianapolis to Charleston without flying?

    You have the option to select the coach for your journey on this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
02/08
No data
03/08
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Today
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05/08
US$562
06/08
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07/08
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08/08
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09/08
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busbud logoThe cheapest trip from Indianapolis to Charleston, SC, US was searched and found on 5 Aug 2025 with a price of US$562

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Charleston, SC, US as early as possible.

You can expect to pay from US$562 to US$862 for a bus ticket from Indianapolis to Charleston, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$562, which is on 2025-08-05.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Indianapolis and Charleston!

Much more than a mere vehicle taking you from Indianapolis to Charleston, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Indianapolis to Charleston that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Indianapolis to Charleston, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

What's the cheapest way to go from Indianapolis to Charleston, SC, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Indianapolis by bus?

Bus from Indianapolis to Charleston, SC, US

You can also go to Charleston, SC, US by train

Train from Indianapolis to Charleston, SC, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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