Bus Tickets from Buffalo, NY to Charleston, SC, US

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TodayAug 7
TomorrowAug 8
SatAug 9
from US$161
SunAug 10
from US$162
MonAug 11
TueAug 12
WedAug 13
from US$164
ThuAug 14

Cheap buses leaving Saturday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: August 9 at
    Departure city: Buffalo
    Departure location: Niagara Frontier Transportation Authority
    Arrival time: August 11 at
    Destination city: Charleston
    Destination location: 4565 Gaynor Ave, North Charleston
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: August 9 at
    Departure city: Buffalo
    Departure location: Buffalo (BUF) Airport
    Arrival time: August 10 at
    Destination city: Charleston
    Destination location: 4565 Gaynor Ave, North Charleston
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 9 at
    Departure city: Buffalo
    Departure location: Niagara Frontier Transportation Authority
    Arrival time: August 10 at
    Destination city: Charleston
    Destination location: 4565 Gaynor Ave, North Charleston
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 9 at
    Departure city: Buffalo
    Departure location: Buffalo (BUF) Airport
    Arrival time: August 11 at
    Destination city: Charleston
    Destination location: 4565 Gaynor Ave, North Charleston
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: August 9 at
    Departure city: Buffalo
    Departure location: Niagara Frontier Transportation Authority
    Arrival time: August 11 at
    Destination city: Charleston
    Destination location: 4565 Gaynor Ave, North Charleston
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Last Saturday at 1:23 PM EDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
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  • China Union Pay
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  • Klarna (Pay over time)
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Compare 2 ways to go from Buffalo to Charleston

Average PriceUS$161 - US$332Average Duration1d 4h
28kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Average PriceUS$205 - US$470Average Duration1d
102kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Buffalo to Charleston

Among the sustainable travel choices, the train stands out as a good way to reach Charleston. The journey takes about 1 day, 13 minutes, and with fares starting at just US$205, it presents an excellent value for a comfortable ride.

2train per day
1d Average Duration
US$205Cheapest ticket
102kgCO₂ emissions

Bus Buffalo, NY to Charleston, SC, US: Trip Overview

Average Ticket PriceUS$188
Average Bus Trip Duration1d 4h
Number of daily buses4
Earliest bus departure10:30am
Distance1124 km
Latest bus departure11:59pm

Buffalo to Charleston Bus

With Busbud, comparing and booking tickets for a bus from Buffalo to Charleston is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Buffalo to Charleston.

From cheap bus tickets to more luxurious buses travelling from Buffalo to Charleston, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Buffalo, NY - Charleston, SC, US

  1. What is the travel distance from Buffalo to Charleston?

    It's about 1129 km (700 miles) from Buffalo to Charleston.

  2. What are the departure and arrival locations for buses traveling from Buffalo to Charleston?

    Buses traveling this route start their trip at Buffalo Airport, in Buffalo, and end it at Charleston Bus Station, in Charleston.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-05
US$191
08-06
No data
Today
No data
08-08
No data
08-09
US$168
08-10
US$176
08-11
No data
08-12
No data
busbud logoThe cheapest trip from Buffalo, NY to Charleston, SC, US was searched and found on Aug 9, 2025 with a price of US$168

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to Charleston, SC, US, as early as possible.

You can expect to pay from US$168 to US$191 for a bus ticket from Buffalo, NY to Charleston, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$168 which is on 2025-08-09.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Buffalo to Charleston.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Buffalo to Charleston.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Buffalo to Charleston that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Buffalo to Charleston, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

What's the cheapest way to go from Buffalo, NY to Charleston, SC, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Buffalo, NY by bus?

Bus from Buffalo, NY to Charleston, SC, US

You can also go to Charleston, SC, US by train

Train from Buffalo, NY to Charleston, SC, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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