Find coaches from Buffalo (NY) to Charleston (SC), US

Find affordable coach tickets from Buffalo (NY) to Charleston (SC), US with flexible options. Book your journey now

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Today15 Jun
from US$163
Tomorrow16 Jun
from US$164
Tue17 Jun
Wed18 Jun
Thu19 Jun
from US$164
Fri20 Jun
from US$164
Sat21 Jun
Sun22 Jun

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 16 June at
    Departure city: Buffalo
    Departure location: Niagara Frontier Transportation Authority
    Arrival time: 18 June at
    Destination city: Charleston
    Destination location: 4565 Gaynor Ave, North Charleston
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 16 June at
    Departure city: Buffalo
    Departure location: Buffalo (BUF) Airport
    Arrival time: 17 June at
    Destination city: Charleston
    Destination location: 4565 Gaynor Ave, North Charleston
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 16 June at
    Departure city: Buffalo
    Departure location: Niagara Frontier Transportation Authority
    Arrival time: 17 June at
    Destination city: Charleston
    Destination location: 4565 Gaynor Ave, North Charleston
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 16 June at
    Departure city: Buffalo
    Departure location: Buffalo (BUF) Airport
    Arrival time: 18 June at
    Destination city: Charleston
    Destination location: 4565 Gaynor Ave, North Charleston
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 16 June at
    Departure city: Buffalo
    Departure location: Buffalo (BUF) Airport
    Arrival time: 17 June at
    Destination city: Charleston
    Destination location: 4565 Gaynor Ave, North Charleston
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to travel from Buffalo to Charleston

Bus
Average priceUS$161 - US$282Average duration1d 14h
28kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average priceUS$205 - US$470Average duration1d
102kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Buffalo to Charleston

Among the sustainable travel choices, the train stands out as a good way to reach Charleston. The journey takes about 1 day, 13 minutes and with fares starting at just US$205, it presents an excellent value for a comfortable ride.

2train per day
1d Average duration
US$205Cheapest ticket
102kgCO₂ emissions

Bus Buffalo to Charleston: Trip Overview

Average ticket priceUS$179
Average bus trip duration1d 14h
Number of daily buses4
Earliest bus departure10:30
Distance693 miles
Latest bus departure23:59

Buffalo to Charleston Bus

With Busbud, comparing and booking tickets for a bus from Buffalo to Charleston is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Buffalo to Charleston.

From cheap bus tickets to more luxurious buses travelling from Buffalo to Charleston, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Buffalo (NY) - Charleston (SC), US

  1. What is the affordable way to go from Buffalo to Charleston?

    The prices typically range from US$161 to US$282 on this trip, with the average ticket costing US$179. The cost of tickets can fluctuate based on factors like the time of day, the company, and the class you choose. Compare the prices and amenities offered by each company on Busbud and find the best deals and offers.

  2. How long does it take to travel from Buffalo to Charleston by bus?

    The average duration for a trip from Buffalo to Charleston by coach is around 1d 14h. If you're looking for the fastest trip, you can get there in just about 1d 4h. However, please keep in mind that your specific travel time may vary due to the prevailing traffic conditions along the route.

  3. When is the first coach from Buffalo to Charleston?

    The first coach to Charleston from Buffalo departs at 10:30. Times and services may vary during weekends and holidays.

  4. How far is Charleston from Buffalo by coach?

    The distance between Buffalo and Charleston by coach is approximately 700 miles (1129 km).

  5. Is there a way to reach Charleston from Buffalo without flying?

    You can choose the coach to travel this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.

  6. Is there am overnight coach from Buffalo to Charleston?

    You can hop on buses departing from Buffalo until 23:59 and reaching Charleston the following day. Remember to bring along some essentials like a snuggly blanket and a few treats for a comfortable trip.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
13/06
No data
14/06
US$191
Today
US$209
16/06
US$175
17/06
No data
18/06
No data
19/06
US$169
20/06
US$208
busbud logoThe cheapest trip from Buffalo to Charleston was searched and found on 19 Jun 2025 with a price of US$169

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo to Charleston as early as possible.

You can expect to pay from US$169 to US$275 for a bus ticket from Buffalo to Charleston based on the last 2 days. You can expect to find the cheapest price for the trip at US$169, which is on 2025-06-19.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Buffalo to Charleston.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Buffalo to Charleston.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Buffalo to Charleston that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Buffalo to Charleston, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

What's the cheapest way to go from Buffalo to Charleston?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Buffalo by bus?

Bus from Buffalo to Charleston

You can also go to Charleston by train

Train from Buffalo to Charleston

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

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