Bus Tickets from Orlando to Charleston, SC, US

Next departures

Next departures for Orlando to Charleston on September 27
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
Orlando Bus Station
4565 Gaynor Ave, North CharlestonCheapest
FlixBus
Orlando Bus Station
4565 Gaynor Ave, North CharlestonFastest

Last refresh of the prices: Today at 12:30 AM EDT.

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Compare 2 ways to go from Orlando to Charleston

Bus
Average PriceUS$41 - US$149Average Duration9h 50m
12kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average PriceUS$63 - US$210Average Duration7h 49m
46kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Orlando to Charleston

Among the sustainable travel choices, the train stands out as a good way to reach Charleston. The journey takes about 7 hours 49 minutes, and with fares starting at just US$63, it presents an excellent value for a comfortable ride.

2train per day
7h 49mAverage Duration
US$63Cheapest ticket
46kgCO₂ emissions

Bus Orlando to Charleston, SC, US: Trip Overview

Average Ticket PriceUS$55
Average Bus Trip Duration9h 50m
Number of daily buses2
Earliest bus departure4:00am
Distance500 km
Latest bus departure6:00am

Orlando to Charleston Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Orlando to Charleston.

We make it our job to connect you with the most dependable bus companies that cover bus service from Orlando to Charleston.

Discover how much the bus trip from Orlando to Charleston will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Orlando - Charleston, SC, US

  1. What is the travel distance from Orlando to Charleston?

    The distance covered from Orlando to Charleston is 493 km (306 miles).

  2. What are the departure and arrival locations for buses traveling from Orlando to Charleston?

    Buses traveling this route start their trip at Orlando Bus Station, in Orlando, and end it at Charleston Bus Station, in Charleston.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09-24
US$116
09-25
US$91
Today
US$57
09-27
US$49
09-28
US$46
09-29
US$42
09-30
US$41
10-01
US$42
busbud logoThe cheapest trip from Orlando to Charleston, SC, US was searched and found on Sep 30, 2025 with a price of US$41

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Charleston, SC, US, as early as possible.

You can expect to pay from US$41 to US$116 for a bus ticket from Orlando to Charleston, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$41 which is on 2025-09-30.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Orlando to Charleston but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Orlando to Charleston.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Orlando to Charleston will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Orlando to Charleston while indulging in miles on end of beautiful scenic views.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

What's the cheapest way to go from Orlando to Charleston, SC, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Orlando by bus?

Bus from Charleston, SC, US to Orlando

You can also go to Charleston, SC, US by train

Train from Orlando to Charleston, SC, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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