Bus Tickets from Columbus, OH to Greenville, SC

Previously seen trips

Next departures for Columbus to Greenville on September 30
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound + FlixBus
100 E Rich St
1116 Woodruff RdNo tags
Greyhound + FlixBus
Columbus Bus Station
1116 Woodruff RdNo tags
Greyhound
Columbus Bus Station
1116 Woodruff RdNo tags
Greyhound
Columbus Bus Station
1116 Woodruff RdNo tags
Greyhound + FlixBus
Columbus Bus Station
1116 Woodruff RdNo tags

Accepted payments

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  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Columbus, OH to Greenville, SC: Trip Overview

Average Ticket PriceUS$91
Average Bus Trip Duration21h 30m
Number of daily buses5
Earliest bus departure12:45am
Distance573 km
Latest bus departure11:30pm

Columbus to Greenville Bus

Busbud helps you find a bus from Columbus to Greenville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Columbus to Greenville from the most reliable bus companies operating this trip.

Discover how much the bus trip from Columbus to Greenville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Columbus, OH - Greenville, SC

  1. How far is Columbus from Greenville?

    It's about 572 km (355 miles) from Columbus to Greenville.

  2. What are the departure and arrival locations for buses traveling from Columbus to Greenville?

    Buses departing from Columbus Bus Station in Columbus will take you to Guadalajara Supermarket Bus Stop in Greenville.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Columbus and Greenville!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Columbus to Greenville, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Columbus to Greenville will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Columbus to Greenville.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Columbus, OH by bus?

Bus from Greenville, SC to Columbus, OH

Why choose Busbud?

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