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One passenger / one way
- This trip is recommended because it is: Cheapest + Fastest
- Departure time: July 18 atDeparture city: Port Saint LucieDeparture location: Port St. Lucie (Park & Ride)Arrival time: July 18 atDestination city: Lake CityDestination location: Lake City Bus StationOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration:
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Bus Port Saint Lucie to Lake City: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Port Saint Lucie to Lake City Bus
With Busbud, comparing and booking tickets for a bus from Port Saint Lucie to Lake City is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
Bus service from Port Saint Lucie to Lake City will be provided by the most trusted bus companies.
Whether it is cheap bus tickets or more luxurious buses going to Lake City from Port Saint Lucie, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Port Saint Lucie and Lake City?
Frequently asked questions for your trip Port Saint Lucie - Lake City
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Port Saint Lucie to Lake City was searched and found on Jul 19, 2025 with a price of $62To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Port Saint Lucie to Lake City, as early as possible.
You can expect to pay from $62 to $75 for a bus ticket from Port Saint Lucie to Lake City based on the last 2 days. You can expect to find the cheapest price for the trip at $62 which is on 2025-07-19.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Port Saint Lucie to Lake City.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Much more than a mere vehicle taking you from Port Saint Lucie to Lake City, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Port Saint Lucie to Lake City.
Tune out to the fine sounds of your best music playlist on your bus trip from Port Saint Lucie to Lake City while indulging in miles on end of beautiful scenic views.
Did you know?
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
Top traveled bus routes
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Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
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Popular Buses Connecting Port Saint Lucie
Buses Leaving from Port Saint Lucie
- Bus from Port Saint Lucie to West Palm Beach
- Bus Port Saint Lucie - Miami
- Port Saint Lucie - Fort Lauderdale
- Bus from Port Saint Lucie to Kissimmee
- Bus Port Saint Lucie - Orlando
- Port Saint Lucie - Tampa
- Bus from Port Saint Lucie to Gainesville
- Bus Port Saint Lucie - Vero Beach
- Port Saint Lucie - Jupiter
- Bus from Port Saint Lucie to Ocala
- Bus Port Saint Lucie - Boca Raton
- Port Saint Lucie - Jacksonville
- Bus from Port Saint Lucie to Sarasota
- Bus Port Saint Lucie - Tallahassee
- Port Saint Lucie - Fort Myers
Buses Going to Port Saint Lucie
- Bus from Fort Pierce to Port Saint Lucie
- Bus Jupiter - Port Saint Lucie
- Tampa - Port Saint Lucie
- Bus from Fort Lauderdale to Port Saint Lucie
- Bus Orlando - Port Saint Lucie
- Miami - Port Saint Lucie
- Bus from Kissimmee to Port Saint Lucie
- Bus West Palm Beach - Port Saint Lucie
- Vero Beach - Port Saint Lucie
- Bus from New York City to Port Saint Lucie
- Bus Fort Myers - Port Saint Lucie
- Jacksonville - Port Saint Lucie
- Bus from Gainesville to Port Saint Lucie
- Bus St. Petersburg - Port Saint Lucie
- Boca Raton - Port Saint Lucie
Popular Buses Connecting Lake City
Buses Leaving from Lake City
- Bus from Lake City to Meridian
- Bus Lake City - Auburn
- Lake City - Houston
- Bus from Lake City to Jacksonville
- Bus Lake City - London
- Lake City - Jacksonville
- Bus from Lake City to Jonesboro
- Bus Lake City - Orlando
- Lake City - Miami
- Bus from Lake City to Chiefland
- Bus Lake City - Tampa
- Lake City - Plant City
- Bus from Lake City to Lakeland
- Bus Lake City - Panama City
- Lake City - Spartanburg
Buses Going to Lake City
- Bus from Ocala to Lake City
- Bus Tallahassee - Lake City
- Anderson - Lake City
- Bus from Orlando to Lake City
- Bus Jacksonville - Lake City
- Denver - Lake City
- Bus from Miami to Lake City
- Bus Gainesville - Lake City
- Tampa - Lake City
- Bus from Atlanta to Lake City
- Bus Myrtle Beach - Lake City
- Florence - Lake City
- Bus from Macon to Lake City
- Bus Dallas - Lake City
- Mobile - Lake City