Bus Tickets from Port Saint Lucie to Lake City

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TodayJul 17
TomorrowJul 18
from US$82
SatJul 19
from US$68
SunJul 20
MonJul 21
TueJul 22
WedJul 23
ThuJul 24

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: July 18 at
    Departure city: Port Saint Lucie
    Departure location: Port St. Lucie (Park & Ride)
    Arrival time: July 18 at
    Destination city: Lake City
    Destination location: Lake City Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 18 at
    Departure city: Port Saint Lucie
    Departure location: Port St. Lucie (Park & Ride)
    Arrival time: July 18 at
    Destination city: Lake City
    Destination location: Lake City Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Yesterday at 10:57 AM EDT.

Prices and availability are subject to change.

Accepted payments

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Bus Port Saint Lucie to Lake City: Trip Overview

Average Ticket PriceUS$86
Average Bus Trip Duration17h 15m
Number of daily buses1
Earliest bus departure3:45pm
Distance391 km

Port Saint Lucie to Lake City Bus

With Busbud, comparing and booking tickets for a bus from Port Saint Lucie to Lake City is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Port Saint Lucie to Lake City will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Lake City from Port Saint Lucie, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Port Saint Lucie - Lake City

  1. How far is Port Saint Lucie from Lake City?

    The distance covered from Port Saint Lucie to Lake City is 392 km (243 miles).

  2. What are the departure and arrival locations for buses traveling from Port Saint Lucie to Lake City?

    Buses traveling this route start their trip at Port St Lucie Mobil Gas Bus Stop, in Port Saint Lucie, and end it at Lake City Bus Stop, in Lake City.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07-15
No data
07-16
No data
Today
US$75
07-18
US$74
07-19
US$62
07-20
No data
07-21
No data
07-22
No data
busbud logoThe cheapest trip from Port Saint Lucie to Lake City was searched and found on Jul 19, 2025 with a price of US$62

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Port Saint Lucie to Lake City, as early as possible.

You can expect to pay from US$62 to US$75 for a bus ticket from Port Saint Lucie to Lake City based on the last 2 days. You can expect to find the cheapest price for the trip at US$62 which is on 2025-07-19.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Port Saint Lucie to Lake City.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Port Saint Lucie to Lake City, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Port Saint Lucie to Lake City.

Tune out to the fine sounds of your best music playlist on your bus trip from Port Saint Lucie to Lake City while indulging in miles on end of beautiful scenic views.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Port Saint Lucie by bus?

Bus from Port Saint Lucie to Lake City

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