Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Parcheggio Via Pietransantina | Terminal Interbus | No tags | ||||
| Bus | Parcheggio Via Pietransantina | Terminal Interbus | No tags | ||||
| Bus | Parcheggio Via Pietransantina | Terminal Interbus | No tags | ||||
| Bus | Parcheggio Via Pietransantina | Terminal Interbus | No tags | ||||
| Bus | Parcheggio Via Pietransantina | Terminal Interbus | No tags |
Get from Pisa to Syracuse
The journey takes about 22 hours 40 minutes and with fares starting at just $113, it presents an excellent value for a comfortable ride.
Where are the popular stops in Pisa and Syracuse?
Stops in Pisa
- AVia Pietrasantina, 56123 Pisa PI
- C
Piazza della Stazione
Piazza della Stazione, 1, 56125 Pisa PI, Italy
Stops in Syracuse
- AViale Paolo Orsi, 20, 96100 Siracusa SR, Italy
- B
Siracusa
Piazzale della Stazione Centrale, 21, 96100 Siracusa SR, Italy - C
Siracusa - Terminal Bus (Stazione FS)
Viale Teocrito, 68-74, 96100 Siracusa SR, Italy
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Pisa to Syracuse by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Pisa to Syracuse?
The cheapest bus tickets from Pisa to Syracuse start from $113. The average price for this route is around $127. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Pisa to Syracuse?
The average bus trip duration from Pisa to Syracuse is 22h 40m, covering a distance of 526 miles (849 km). The quickest bus can get you there in 22h 40m and is operated by FlixBus.
Which bus companies service the Pisa to Syracuse route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Pisa to Syracuse?
The earliest bus departs from Pisa to Syracuse at 4:55pm. And the latest bus departs at 10:00pm.
What are the CO₂ emissions for the bus trip from Pisa to Syracuse?
A bus trip from Pisa to Syracuse generates an estimated 21 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Pisa to Syracuse was searched and found on Nov 29, 2025 with a price of $124To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pisa to Syracuse, as early as possible.
