Among the sustainable travel choices, the carpool stands out as the good way to reach Rome. The journey takes about 3 hours 50 minutes and with fares starting at just $15, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 158 reviews, the company was rated 4 stars on Busbud. Travelers were especially satisfied with the staff and the ticket access but often complained with the timeliness. BusItalia ticket prices on this trip start at $37
Based on 892 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the staff and the temperature but often complained with the wifi. MarinoBus ticket prices on this trip start at $22
Based on 942 reviews, the company was rated 3.8 stars on Busbud. Travelers were especially satisfied with the ticket access and the temperature but often complained with the timeliness. Itabus ticket prices on this trip start at $15
Based on 140 reviews, the company was rated 4.6 stars on Busbud. Travelers were especially satisfied with the cleanliness and the ticket access but often complained with the power outlets. GoOpti ticket prices on this trip start at $1,012
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Pisa to Rome by bus
What is the distance between Pisa and Rome?
Pisa and Rome are 165 miles (265 km) apart.
What are the departure and arrival stations when taking the bus from Pisa to Rome?
If you're headed to Rome from Pisa, chances are that your bus will depart from Parcheggio Via Pietransantina and arrive at Rome Ciampino Airport. These are the main departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.
What are the best sights and things to do in Rome?
Once in Rome, you can start exploring the city and discover its surroundings. The top sights and things to do are The Vatican City, Museo di Roma, Teatro dell'Opera di Roma, Domus Aurea – Nero’s Golden House and Piazza Navona.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/14
$38
11/15
$35
Today
$20
11/17
$16
11/18
$14
11/19
$20
11/20
$14
11/21
$14
The cheapest trip from Pisa to Rome was searched and found on Nov 18, 2025 with a price of $14
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pisa to Rome, as early as possible.
You can expect to pay from $14 to $146 for a bus ticket from Pisa to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at $14 which is on 2025-11-18.
Usually BusItalia, FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Pisa to Rome?
The bus is the cheapest travel choice for this destination
The cheapest trip from Pisa to Rome was searched and found on Nov 18, 2025 with a price of $14
The bus is the cheapest travel choice for this destination
