Among the sustainable travel choices, the carpool stands out as the good way to reach Rome. The journey takes about 3 hours 50 minutes and with fares starting at just $17, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 930 reviews, the company was rated 3.8 stars on Busbud. Travelers were especially satisfied with the ticket access and the temperature but often complained with the timeliness. Itabus ticket prices on this trip start at $15
Based on 155 reviews, the company was rated 4 stars on Busbud. Travelers were especially satisfied with the staff and the ticket access but often complained with the timeliness. BusItalia ticket prices on this trip start at $37
Based on 879 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the staff and the temperature but often complained with the wifi. MarinoBus ticket prices on this trip start at $22
Based on 140 reviews, the company was rated 4.6 stars on Busbud. Travelers were especially satisfied with the cleanliness and the ticket access but often complained with the power outlets. GoOpti ticket prices on this trip start at $1,012
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
With Busbud, comparing and booking tickets for a bus from Pisa to Rome is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make it our job to connect you with the most dependable bus companies that cover bus service from Pisa to Rome.
From cheap bus tickets to more luxurious buses traveling from Pisa to Rome, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Via Vincenzo Giudice, 00173 Roma RM, ItalyAnagnina
Frequently asked questions for your trip Pisa - Rome
What is the distance between Pisa and Rome?
Pisa and Rome are 165 miles (265 km) apart.
What are the departure and arrival stations when taking the bus from Pisa to Rome?
If you're headed to Rome from Pisa, chances are that your bus will depart from Parcheggio Via Pietransantina and arrive at Rome Tiburtina Bus Station. These are the main departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.
What are the best sights and things to do in Rome?
Once in Rome, you can start exploring the city and discover its surroundings. The top sights and things to do are The Vatican City, Museo di Roma, Teatro dell'Opera di Roma, Domus Aurea – Nero’s Golden House and Piazza Navona.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
09/27
$42
09/28
$43
Today
$17
09/30
$16
10/01
$20
10/02
$15
10/03
$16
10/04
$14
The cheapest trip from Pisa to Rome was searched and found on Oct 4, 2025 with a price of $14
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pisa to Rome, as early as possible.
You can expect to pay from $14 to $147 for a bus ticket from Pisa to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at $14 which is on 2025-10-04.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Pisa to Rome.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Pisa to Rome.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Pisa to Rome that are otherwise impossible to come by with a plane.
Make a music playlist for your bus ride from Pisa to Rome, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
What's the cheapest way to go from Pisa to Rome?
The bus is the cheapest travel choice for this destination
Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
Busbud recommends carpooling from Pisa to Rome
The cheapest trip from Pisa to Rome was searched and found on Oct 4, 2025 with a price of $14
The bus is the cheapest travel choice for this destination
