What is the travel distance from Philadelphia to Florence?

About 467 miles (753 km) separate Philadelphia and Florence.

What are the departure and arrival stations when taking the bus from Philadelphia to Florence?

The majority of buses traveling from Philadelphia to Florence start their journey at Philadelphia Airport and wind up at Florence Bus Station. These are the main departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.

What are the best sights and things to do in Florence?

Once in Florence, you can start exploring the city and discover its surroundings. The top sights and things to do are Palazzo Pitti, Tuscan Wine Tour, Museo Galileo - Institute and Museum of the History of Science, Leonardo Da Vinci Museum and Galleria degli Uffizi.

Bus Philadelphia to Florence from $64 | Refundable Tickets

Next bus departures

Next departures for Philadelphia to Florence on November 13
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	8:30pm	199 Spring Garden St.	15h 15m	11:45am	Bus station	Cheapest
	Bus	6:30pm	Philadelphia, 199 Spring Garden St	11h 15m	5:45am	Florence, SC	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	5:50pm	199 Spring Garden St.	11h 55m	5:45am	Florence, SC	No tags
	Bus	11:00am	Cherry Hill Mall	18h 45m	5:45am	Florence, SC	No tags
	Bus	8:00pm	Schuylkill & Walnut	15h 45m	11:45am	Bus station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	6:45pm	Philadelphia, 199 Spring Garden St	17h	11:45am	Bus station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	7:05pm	Cherry Hill Mall	16h 40m	11:45am	Bus station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	2:00pm	Philadelphia (Logan Square)	21h 45m	11:45am	Bus station	No tags

Next departures for Philadelphia to Florence on November 14
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	10:00pm	Philadelphia, 199 Spring Garden St	13h 45m	11:45am	Bus station	Cheapest
	Bus	6:30pm	Philadelphia, 199 Spring Garden St	11h 15m	5:45am	Florence, SC	Fastest
	Bus	8:30pm	199 Spring Garden St.	15h 15m	11:45am	Bus station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	5:50pm	199 Spring Garden St.	11h 55m	5:45am	Florence, SC	No tags
	Bus	11:00am	Cherry Hill Mall	18h 45m	5:45am	Florence, SC	No tags
FlixBus + Greyhound Lines, Inc.	Bus	7:05pm	Cherry Hill Mall	16h 40m	11:45am	Bus station	No tags
	Bus	8:00pm	Schuylkill & Walnut	15h 45m	11:45am	Bus station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	2:00pm	Philadelphia (Logan Square)	21h 45m	11:45am	Bus station	No tags

Next departures for Philadelphia to Florence on November 15
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	10:00pm	Philadelphia, 199 Spring Garden St	13h 45m	11:45am	Bus station	Cheapest
	Bus	6:30pm	Philadelphia, 199 Spring Garden St	11h 15m	5:45am	Florence, SC	Fastest
	Bus	8:30pm	199 Spring Garden St.	15h 15m	11:45am	Bus station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	5:50pm	199 Spring Garden St.	11h 55m	5:45am	Florence, SC	No tags
	Bus	11:00am	Cherry Hill Mall	18h 45m	5:45am	Florence, SC	No tags
FlixBus + Greyhound Lines, Inc.	Bus	7:05pm	Cherry Hill Mall	16h 40m	11:45am	Bus station	No tags
	Bus	8:00pm	Schuylkill & Walnut	15h 45m	11:45am	Bus station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	2:00pm	Philadelphia (Logan Square)	21h 45m	11:45am	Bus station	No tags

Next departures for Philadelphia to Florence on November 16
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	8:30pm	199 Spring Garden St.	15h 15m	11:45am	Bus station	Cheapest
	Bus	6:30pm	Philadelphia, 199 Spring Garden St	11h 15m	5:45am	Florence, SC	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	5:50pm	199 Spring Garden St.	11h 55m	5:45am	Florence, SC	No tags
	Bus	11:00am	Cherry Hill Mall	18h 45m	5:45am	Florence, SC	No tags
	Bus	8:00pm	Schuylkill & Walnut	15h 45m	11:45am	Bus station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	10:00pm	Philadelphia, 199 Spring Garden St	13h 45m	11:45am	Bus station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	7:05pm	Cherry Hill Mall	16h 40m	11:45am	Bus station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	2:00pm	Philadelphia (Logan Square)	21h 45m	11:45am	Bus station	No tags

Last refresh of the prices: Today at 7:04 AM EST.

Compare 2 ways to go from Philadelphia to Florence

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Florence. The journey takes about 10 hours 55 minutes and with fares starting at just $91, it presents an excellent value for a comfortable ride.

1train per day

10h 55mAverage Duration

470 milesDistance

69kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$64 - $169	Average Duration16h 20m	CO₂ emissions 19kg CO₂e
Train	Average Price$91 - $312	Average Duration10h 55m	CO₂ emissions 69kg CO₂e

Compare bus companies

FlixBus

3.5/511,292 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,370 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in Philadelphia and Florence?

Stops in Philadelphia

A - Philadelphia Airport

B - Independence Travel Center

C - #2842 St.Vincent St

D - Bus Station

E - Island Av & Suffolk Av MBFS

F - NRG SEPTA Station

Stops in Florence

A - Florence Bus Station

B - TA Travel Center - Florence

Frequently asked questions about traveling from Philadelphia, PA to Florence, SC, US by bus

What is the travel distance from Philadelphia to Florence?
What are the departure and arrival stations when taking the bus from Philadelphia to Florence?
What are the best sights and things to do in Florence?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/10

$118

11/11

$78

Today

$136

11/13

$114

11/14

$89

11/15

$78

11/16

$81

11/17

$71

The cheapest trip from Philadelphia, PA to Florence, SC, US was searched and found on Nov 17, 2025 with a price of $71

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to Florence, SC, US, as early as possible.

You can expect to pay from $71 to $139 for a bus ticket from Philadelphia, PA to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $71 which is on 2025-11-17.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.