Bus from Philadelphia, PA to Florence, SC, US: Tickets & Timetables

Next bus departures

Next departures from Philadelphia to Florence on 2 December
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.Bus
Schuylkill & Walnut
Bus stationCheapest
FlixBus + Greyhound Lines, Inc.
Bus
Philadelphia, 199 Spring Garden St
Bus stationFastest
Greyhound Lines, Inc.Bus
199 Spring Garden St.
Bus stationNo tags
FlixBus + Greyhound Lines, Inc.
Bus
Philadelphia (Logan Square)
Bus stationNo tags
Greyhound Lines, Inc.Bus
Camden (Walter Rand Transportation Center)
Bus stationNo tags

Last refresh of the prices: Yesterday at 10:51 EST.

Compare 2 ways to travel from Philadelphia to Florence

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Florence. The journey takes about 10 hours 22 minutes and with fares starting at just £70, it presents an excellent value for a comfortable ride.

2train per day
10h 22mAverage duration
470 milesDistance
69kgCO₂ emissions
Average price£46 - £237Average duration16h 5m
19kg CO₂e
Average price£70 - £242Average duration10h 22m
69kg CO₂e

Frequently asked questions about travelling by bus from Philadelphia, PA to Florence, SC, US

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

  1. How much is the bus ticket from Philadelphia to Florence?

    The cheapest coach tickets from Philadelphia to Florence start from £46. The average price for this route is around £77. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus journey from Philadelphia to Florence?

    The average bus journey time from Philadelphia to Florence is 16h 5m, covering a distance of 473 miles. The fastest bus can take you there in 10h 15m and is operated by FlixBus.

  3. Which bus companies service the Philadelphia to Florence route?

    Several major bus companies operate on this route with 12 buses available per day, including services from Greyhound, FlixBus.

  4. What is the earliest and latest departure time for the bus from Philadelphia to Florence?

    The earliest bus departs from Philadelphia to Florence at 10:40. And the latest bus departs at 23:15.

  5. What are the CO₂ emissions for the bus trip from Philadelphia to Florence?

    A bus journey from Philadelphia to Florence produces an estimated 19 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

  6. Which is the best bus company from Philadelphia to Florence?

    According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.

  7. Which company has the best Wi-Fi from Philadelphia to Florence?

    Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

  8. Which bus company offers the most punctual service from Philadelphia to Florence?

    According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Philadelphia to Florence?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
29/11
£167
30/11
£96
Today
£149
02/12
£110
03/12
£63
04/12
£58
05/12
£60
06/12
£54
busbud logoThe cheapest trip from Philadelphia, PA to Florence, SC, US was searched and found on 6 Dec 2025 with a price of £54

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to Florence, SC, US as early as possible.

You can expect to pay from £54 to £190 for a bus ticket from Philadelphia, PA to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at £54, which is on 2025-12-06.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

What's the cheapest way to go from Philadelphia, PA to Florence, SC, US?

busbud logoThe bus is the cheapest travel choice for this destination

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