Bus Tickets from Orlando to San Antonio, US

Next bus departures

Next departures for Orlando to San Antonio on November 16
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
The Florida Mall
San Antonio Bus StationCheapest
FlixBus + Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Orlando Bus Station
San Antonio Bus StationFastest
Greyhound Lines, Inc. + FlixBus
Bus
Orlando Bus Station
San Antonio Bus StationNo tags
FlixBus + Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Orlando Bus Station
San Antonio Bus StationNo tags
Greyhound Lines, Inc. + FlixBus
Bus
Orlando Bus Station
Pearl DistrictNo tags

Last refresh of the prices: Last Monday at 7:15 PM EST.

Get from Orlando to San Antonio

This route is served by bus only

The journey takes about 1 day, 10 hours and with fares starting at just $102, it presents an excellent value for a comfortable ride.

5bus per day
1d 10hAverage Duration
1031 milesDistance
42kgCO₂ emissions

Frequently asked questions about traveling from Orlando to San Antonio, US by bus

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/12
No data
11/13
$125
Today
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11/15
No data
11/16
No data
11/17
No data
11/18
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11/19
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busbud logoThe cheapest trip from Orlando to San Antonio, US was searched and found on Nov 13, 2025 with a price of $125

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to San Antonio, US, as early as possible.

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