Next departures for Milano to Palermo on December 1
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Piazza I Maggio, 1
Terminal Bus Palermo
CheapestFastest
Next departures for Milano to Palermo on December 2
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Aeroporto Linate Airport (LIN)
Terminal Bus Palermo
Cheapest
Bus
Lampugnano bus station
Terminal Bus Palermo
Fastest
Bus
Lampugnano bus station
Terminal Bus Palermo
No tags
Bus
Milan (San Donato M3)
Terminal Bus Palermo
No tags
Bus
Piazza I Maggio, 1
Terminal Bus Palermo
No tags
Next departures for Milano to Palermo on December 3
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Lampugnano bus station
Terminal Bus Palermo
Cheapest
Bus
Milan San Donato Bus Station
Terminal Bus Palermo
Fastest
Bus
Lampugnano
Terminal Bus Palermo
No tags
Bus
Milan (San Donato M3)
Terminal Bus Palermo
No tags
Bus
Milan (Assago M2)
Terminal Bus Palermo
No tags
Next departures for Milano to Palermo on December 4
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Lampugnano bus station
Terminal Bus Palermo
Cheapest
Bus
Milan San Donato Bus Station
Terminal Bus Palermo
Fastest
Bus
Lampugnano
Terminal Bus Palermo
No tags
Bus
Milan (San Donato M3)
Terminal Bus Palermo
No tags
Bus
Piazza I Maggio, 1
Terminal Bus Palermo
No tags
Next departures for Milano to Palermo on December 5
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Aeroporto Linate Airport (LIN)
Terminal Bus Palermo
Cheapest
Bus
Milan San Donato Bus Station
Terminal Bus Palermo
Fastest
Bus
Lampugnano
Terminal Bus Palermo
No tags
Bus
Lampugnano bus station
Terminal Bus Palermo
No tags
Bus
Lampugnano bus station
Terminal Bus Palermo
No tags
Next departures for Milano to Palermo on December 6
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Aeroporto Linate Airport (LIN)
Terminal Bus Palermo
Cheapest
Bus
Milan San Donato Bus Station
Terminal Bus Palermo
Fastest
Bus
Lampugnano
Terminal Bus Palermo
No tags
Bus
Lampugnano bus station
Terminal Bus Palermo
No tags
Bus
Lampugnano bus station
Terminal Bus Palermo
No tags
Next departures for Milano to Palermo on December 7
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Aeroporto Linate Airport (LIN)
Terminal Bus Palermo
Cheapest
Bus
Milan San Donato Bus Station
Terminal Bus Palermo
Fastest
Bus
Lampugnano
Terminal Bus Palermo
No tags
Bus
Lampugnano bus station
Terminal Bus Palermo
No tags
Bus
Lampugnano bus station
Terminal Bus Palermo
No tags
Next departures for Milano to Palermo on December 8
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Aeroporto Linate Airport (LIN)
Terminal Bus Palermo
Cheapest
Bus
Milan San Donato Bus Station
Terminal Bus Palermo
Fastest
Bus
Lampugnano
Terminal Bus Palermo
No tags
Bus
Lampugnano bus station
Terminal Bus Palermo
No tags
Bus
Lampugnano bus station
Terminal Bus Palermo
No tags
Last refresh of the prices: Today at 4:04 PM CET.
Compare 2 ways to go from Milano to Palermo
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as the good way to reach Palermo. The journey takes about 16 hours 40 minutes and with fares starting at just $79, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 453 reviews, the company was rated 4.3 stars on Busbud. Travelers were especially satisfied with the ticket access and the staff but often complained with the wifi. Autoservizi Salemi ticket prices on this trip start at $100
Based on 948 reviews, the company was rated 3.8 stars on Busbud. Travelers were especially satisfied with the ticket access and the temperature but often complained with the timeliness. Itabus ticket prices on this trip start at $118
Frequently asked questions about traveling from Milano to Palermo by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Milano to Palermo?
The cheapest bus tickets from Milano to Palermo start from $36. The average price for this route is around $109. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Milano to Palermo?
The average bus trip duration from Milano to Palermo is 1d 2h, covering a distance of 547 miles (883 km). The quickest bus can get you there in 21h and is operated by Autoservizi Salemi.
Which bus companies service the Milano to Palermo route?
Several major bus companies operate on this route with 11 buses available per day, including services from FlixBus, Autoservizi Salemi, Itabus.
What is the earliest and latest departure time for the bus from Milano to Palermo?
The earliest bus departs from Milano to Palermo at 12:00am. And the latest bus departs at 11:50pm.
What are the CO₂ emissions for the bus trip from Milano to Palermo?
A bus trip from Milano to Palermo generates an estimated 22 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Milano to Palermo?
According to Busbud customers, the highest-rated bus company on this route is Autoservizi Salemi, with an average rating of 4.3 out of 5 stars based on 450 reviews.
Which bus company has the best Wi-Fi from Milano to Palermo?
Based on reviews on Busbud, the bus company Autoservizi Salemi has the best Wi-Fi rating with a score of 3.9.
Which bus company has the most timely service from Milano to Palermo?
According to Busbud traveller reviews, the most timely bus company on this route is Autoservizi Salemi, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Milano to Palermo?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Autoservizi Salemi, with a cleanliness rating of 4.7 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/29
$157
11/30
$188
Today
$170
12/02
$89
12/03
$89
12/04
$79
12/05
$87
12/06
$85
The cheapest trip from Milano to Palermo was searched and found on Dec 4, 2025 with a price of $79
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milano to Palermo, as early as possible.
You can expect to pay from $79 to $188 for a bus ticket from Milano to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at $79 which is on 2025-12-04.