Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Flix México + Greyhound Lines Mexico + Greyhound Lines, Inc. | Mexico City Buenavista (San Pedro Santa Clara) | Panama City Beach Station | Cheapest | |||||
Flix México + Greyhound Lines Mexico + Greyhound Lines, Inc. | Mexico City Buenavista (Forum) | Panama City Beach Station | Fastest |
Last refresh of the prices: Yesterday at 10:05 AM CST.
Accepted payments
Bus Mexico City to Panama City, US: Trip Overview
Mexico City to Panama City Bus
Busbud helps you find a bus from Mexico City to Panama City. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make sure you can find a bus service from Mexico City to Panama City from the most reliable bus companies operating this trip.
Whether it is cheap bus tickets or more luxurious buses going to Panama City from Mexico City, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Mexico City and Panama City?
Frequently asked questions for your trip Mexico City - Panama City, US
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Mexico City and Panama City!
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Mexico City to Panama City, get comfy and count the stars.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Mexico City to Panama City.
Tune out to the fine sounds of your best music playlist on your bus trip from Mexico City to Panama City while indulging in miles on end of beautiful scenic views.
Did you know?
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
Top traveled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
People from around the world trust Busbud
Popular Buses Connecting Mexico City
Buses Leaving from Mexico City
- Bus from Mexico City to Cancún
- Bus Mexico City - Centro
- Mexico City - Denver
- Bus from Mexico City to Tulum
- Bus Mexico City - Acapulco
- Mexico City - Guanajuato
- Bus from Mexico City to Santiago de Querétaro
- Bus Mexico City - Guadalajara
- Mexico City - Taxco
- Bus from Mexico City to Cuernavaca
- Bus Mexico City - Morelia
- Mexico City - Puerto Vallarta
- Bus from Mexico City to Tijuana
- Bus Mexico City - Toluca
- Mexico City - San Luis Potosí
Buses Going to Mexico City
- Bus from Chicago to Mexico City
- Bus Miami - Mexico City
- Austin - Mexico City
- Bus from San Juan to Mexico City
- Bus Dixon - Mexico City
- Temple - Mexico City
- Bus from Guadalajara to Mexico City
- Bus San Miguel de Allende - Mexico City
- Santiago de Querétaro - Mexico City
- Bus from Tijuana to Mexico City
- Bus Cancún - Mexico City
- Monterrey - Mexico City
- Bus from Puerto Vallarta to Mexico City
- Bus Guanajuato - Mexico City
- Cuernavaca - Mexico City
Popular Buses Connecting Panama City
Buses Leaving from Panama City
- Bus from Panama City to Long Beach
- Bus Panama City - Miami
- Panama City - San Jose
- Bus from Panama City to Atlanta
- Bus Panama City - Tallahassee
- Panama City - Gainesville
- Bus from Panama City to Orlando
- Bus Panama City - Tampa
- Panama City - Fort Lauderdale
- Bus from Panama City to Jacksonville
- Bus Panama City - Biloxi
- Panama City - New Orleans
- Bus from Panama City to Gainesville
- Bus Panama City - New York City
- Panama City - Dothan
Buses Going to Panama City
- Bus from Miami to Panama City
- Bus Tallahassee - Panama City
- Atlanta - Panama City
- Bus from Tampa to Panama City
- Bus Chicago - Panama City
- San Jose - Panama City
- Bus from Orlando to Panama City
- Bus Fort Lauderdale - Panama City
- Jacksonville - Panama City
- Bus from Houston to Panama City
- Bus Dothan - Panama City
- New Orleans - Panama City
- Bus from New York City to Panama City
- Bus Birmingham - Panama City
- Dallas - Panama City
Popular routes in this country
- Bus from Puerto Escondido to Oaxaca
- Bus Tulum - Cancún
- Cancún - Mérida
- Bus from Mérida to Cancún
- Bus Cancún - Chiquilá
- Playa del Carmen - Cancún
- Bus from Mexico City to San Miguel de Allende
- Bus Chiquilá - Cancún
- Guadalajara - Puerto Vallarta
- Bus from Playa del Carmen to Tulum
- Bus Puebla - Oaxaca
- Oaxaca - San Cristóbal de las Casas
- Bus from Mexico City to Puerto Escondido
- Bus Puebla - Mexico City
- Puerto Escondido - Mexico City