Based on 78 reviews, the company was rated 4 stars on Busbud. Travelers were especially satisfied with the departure location and the cleanliness but often complained with the wifi. Pluss Chile ticket prices on this trip start at $34
Based on 124 reviews, the company was rated 3.7 stars on Busbud. Travelers were especially satisfied with the staff and the ticket access but often complained with the wifi. Cikbus Elité ticket prices on this trip start at $29
Based on 54 reviews, the company was rated 4.2 stars on Busbud. Travelers were especially satisfied with the ticket access and the seats but often complained with the wifi. Buses Andimar ticket prices on this trip start at $34
Based on 13 reviews, the company was rated 3.6 stars on Busbud. Travelers were especially satisfied with the seats and the temperature but often complained with the timeliness. Pullman San Andres ticket prices on this trip start at $59
Based on 50 reviews, the company was rated 3.8 stars on Busbud. Travelers were especially satisfied with the ticket access and the seats but often complained with the wifi. Buses Romani ticket prices on this trip start at $56
Based on 19 reviews, Condor Bus was rated 3.6 stars for this trip. Condor Bus ticket prices on this trip start at $58, with the trip lasting on average 1235.
Based on 12 reviews, Serena Mar was rated 4 stars for this trip. Serena Mar ticket prices on this trip start at $43, with the trip lasting on average 1255.
Based on 3 reviews, the company was rated 4.3 stars on Busbud. Travelers were especially satisfied with the staff and the timeliness but often complained with the wifi. Clikbus ticket prices on this trip start at $28
Panamericana Norte 208, La Serena, Región de Coquimbo, Chile
Stops in Calama
A - Av. Balmaceda
Av. Balmaceda 1940, Calama, Región de Antofagasta, ChileAv. Balmaceda
B - Calama
Antofagasta 2046, Calama, El Loa 1390714, Antofagasta, Chile
C - Parada de Autobuses de Calama - Ascotan
Ascotán 1891, Calama, Región de Antofagasta, Chile
D - Parada de Autobuses de Calama - Cebollar
Cebollar 1864, Calama, Región de Antofagasta, Chile
E - Terminal: Sub Agencia Avda. Balmaceda
Terminal: Sub Agencia Avda. Balmaceda, Calle O'Higgins O 681, Villa - Caspana, Calama, Antofagasta, Chile
F - Terminal Pullman Bus de Calama
Av. Balmaceda 1802, Calama, Región de Antofagasta, Chile
Frequently asked questions about traveling from La Serena, CL to Calama by bus
How far is La Serena from Calama?
La Serena and Calama are 534 miles (861 km) apart.
What are the departure and arrival stations when taking the bus from La Serena to Calama?
Most of the buses traveling from La Serena to Calama leave from Terminal de Buses La Serena and arrive at Av. Balmaceda. These are the most popular pick-up and drop-off locations on this route, but you could find others that could be a better fit for your travel plans.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/12
$28
11/13
$28
Today
$33
11/15
$32
11/16
$32
11/17
$28
11/18
$33
11/19
$28
The cheapest trip from La Serena, CL to Calama was searched and found on Nov 19, 2025 with a price of $28
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from La Serena, CL to Calama, as early as possible.
You can expect to pay from $28 to $48 for a bus ticket from La Serena, CL to Calama based on the last 2 days. You can expect to find the cheapest price for the trip at $28 which is on 2025-11-19.
Usually Pluss Chile will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.