Bus Tickets from Knoxville, TN to Roanoke

Previously seen trips

Next departures for Knoxville to Roanoke on September 28
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
Knoxville Bus Station
Roanoke Bus StopNo tags
Greyhound
Knoxville Bus Station
Roanoke Bus StopNo tags
Greyhound
Knoxville Bus Station
Roanoke Bus StopNo tags
Greyhound
Knoxville Bus Station
Roanoke Bus StopNo tags
Greyhound
Knoxville Bus Station
Roanoke Bus StopNo tags

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Bus Knoxville, TN to Roanoke: Trip Overview

Average ticket price$46
Average bus trip duration5h 5m
Number of daily buses1
Earliest bus departure10:50pm
Distance235 miles (378 km)

Knoxville to Roanoke Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Knoxville to Roanoke.

We make it our job to connect you with the most dependable bus companies that cover bus service from Knoxville to Roanoke.

Whether it is cheap bus tickets or more luxurious buses going to Roanoke from Knoxville, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Knoxville, TN - Roanoke

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/26
No data
09/27
No data
Today
$40
09/29
$38
09/30
No data
10/01
$38
10/02
No data
10/03
$38
busbud logoThe cheapest trip from Knoxville, TN to Roanoke was searched and found on Sep 29, 2025 with a price of $38

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Roanoke, as early as possible.

You can expect to pay from $38 to $40 for a bus ticket from Knoxville, TN to Roanoke based on the last 2 days. You can expect to find the cheapest price for the trip at $38 which is on 2025-09-29.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Knoxville to Roanoke but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Knoxville to Roanoke.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Knoxville to Roanoke.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Knoxville to Roanoke.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Knoxville, TN by bus?

Bus from Roanoke to Knoxville, TN

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