Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Jefferson City | Knoxville Bus Station | No tags | |||||
| Jefferson City | Knoxville Bus Station | No tags | |||||
| Jefferson City | 100 Kirkwood St | No tags | |||||
| Jefferson City | Knoxville Bus Station | No tags | |||||
| Jefferson City | 100 Kirkwood St | No tags |
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Bus Jefferson City, MO to Knoxville, TN: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Jefferson City to Knoxville Bus
Busbud helps you find a bus from Jefferson City to Knoxville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Jefferson City to Knoxville.
Discover how much the bus trip from Jefferson City to Knoxville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Frequently asked questions for your trip Jefferson City, MO - Knoxville, TN
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Jefferson City, MO to Knoxville, TN was searched and found on Oct 3, 2025 with a price of $79To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jefferson City, MO to Knoxville, TN, as early as possible.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Jefferson City and Knoxville!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Jefferson City to Knoxville.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Jefferson City to Knoxville will emit less CO2 than a car or an airplane.
Make a music playlist for your bus ride from Jefferson City to Knoxville, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.
Top traveled bus routes
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Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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Popular Buses Connecting Jefferson City
Buses Leaving from Jefferson City
- Bus from Jefferson City to Oklahoma City
- Bus Jefferson City - St. Louis
- Jefferson City - Columbia
- Bus from Jefferson City to Springfield
- Bus Jefferson City - Kansas City
- Jefferson City - Indianapolis
- Bus from Jefferson City to Orlando
- Bus Jefferson City - Memphis
- Jefferson City - New York City
- Bus from Jefferson City to Dallas
- Bus Jefferson City - Jackson
- Jefferson City - Jacksonville
- Bus from Jefferson City to Atlanta
- Bus Jefferson City - Madison
- Jefferson City - Chicago
Buses Going to Jefferson City
- Bus from Knoxville to Jefferson City
- Bus Columbia - Jefferson City
- St. Louis - Jefferson City
- Bus from Kansas City to Jefferson City
- Bus Houston - Jefferson City
- Buffalo - Jefferson City
- Bus from Chicago to Jefferson City
- Bus New York City - Jefferson City
- Champaign - Jefferson City
- Bus from Indianapolis to Jefferson City
- Bus Denver - Jefferson City
- Washington - Jefferson City
- Bus from Los Angeles to Jefferson City
- Bus Atlanta - Jefferson City
- Springfield - Jefferson City
Popular Buses Connecting Knoxville
Buses Leaving from Knoxville
- Bus from Knoxville to Charlotte
- Bus Knoxville - Marathon
- Knoxville - Lexington
- Bus from Knoxville to Chicago
- Bus Knoxville - Orlando
- Knoxville - Greenville
- Bus from Knoxville to Nashville
- Bus Knoxville - Atlanta
- Knoxville - Memphis
- Bus from Knoxville to New York City
- Bus Knoxville - Washington
- Knoxville - Asheville
- Bus from Knoxville to Miami
- Bus Knoxville - Jackson
- Knoxville - Cincinnati
Buses Going to Knoxville
- Bus from Nashville to Knoxville
- Bus Memphis - Knoxville
- Charlotte - Knoxville
- Bus from Chicago to Knoxville
- Bus Tampa - Knoxville
- Detroit - Knoxville
- Bus from Atlanta to Knoxville
- Bus New York City - Knoxville
- Asheville - Knoxville
- Bus from Louisville to Knoxville
- Bus Greenville - Knoxville
- Lexington - Knoxville
- Bus from Dallas to Knoxville
- Bus Cookeville - Knoxville
- Dayton - Knoxville
Popular routes in this country
- Bus from Fort Lauderdale to Orlando
- Bus Dallas - Houston
- Albany - New York City
- Bus from Las Vegas to Los Angeles
- Bus Tampa - Miami
- Austin - Dallas
- Bus from Dallas to Austin
- Bus Seattle - Leavenworth
- Miami - Tampa
- Bus from Austin to Houston
- Bus Houston - San Antonio
- Houston - Austin
- Bus from San Antonio to Houston
- Bus Orlando - Atlanta
- Atlanta - Orlando