Bus Tickets from Greenville, SC to Jacksonville, FL

Next departures

Next departures for Greenville to Jacksonville on October 3
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
1116 Woodruff Rd
Jacksonville Bus StationCheapest
FlixBus
1116 Woodruff Rd
Jacksonville Bus StationFastest
FlixBus
1116 Woodruff Rd
Jacksonville Bus StationNo tags

Last refresh of the prices: Last Friday at 1:49 PM EDT.

Accepted payments

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Compare 2 ways to go from Greenville to Jacksonville.

Bus
Average Price$58 - $133Average Duration11h 40m
13kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$140 - $1,330Average Duration1d 4h
46kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Greenville to Jacksonville

Among the sustainable travel choices, the bus stands out as the good way to reach Jacksonville. The journey takes about 11 hours 40 minutes and with fares starting at just $58, it presents an excellent value for a comfortable ride.

2bus per day
11h 40mAverage Duration
$58Cheapest ticket
13kgCO₂ emissions

Bus Greenville, SC to Jacksonville, FL: Trip Overview

Average ticket price$89
Average bus trip duration11h 40m
Number of daily buses2
Earliest bus departure8:40am
Distance313 miles (504 km)
Latest bus departure10:00pm

Greenville to Jacksonville Bus

Busbud helps you find a bus from Greenville to Jacksonville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Greenville to Jacksonville.

Discover how much the bus trip from Greenville to Jacksonville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Greenville, SC - Jacksonville, FL

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/30
$86
10/01
$102
Today
$51
10/03
$52
10/04
No data
10/05
$79
10/06
No data
10/07
No data
busbud logoThe cheapest trip from Greenville, SC to Jacksonville, FL was searched and found on Oct 2, 2025 with a price of $51

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Jacksonville, FL, as early as possible.

You can expect to pay from $51 to $120 for a bus ticket from Greenville, SC to Jacksonville, FL based on the last 2 days. You can expect to find the cheapest price for the trip at $52 which is on 2025-10-03.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Greenville and Jacksonville!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Greenville to Jacksonville.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Greenville to Jacksonville will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Greenville to Jacksonville.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

What's the cheapest way to go from Greenville, SC to Jacksonville, FL?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Greenville, SC by bus?

Bus from Jacksonville, FL to Greenville, SC

You can also go to Jacksonville, FL by train

Train from Greenville, SC to Jacksonville, FL

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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