Find coaches from Greenville, SC to Jacksonville, FL

Find affordable coach tickets from Greenville, SC to Jacksonville, FL with flexible options. Book your journey now

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Today7 Aug
Tomorrow8 Aug
Sat9 Aug
Sun10 Aug
Mon11 Aug
Tue12 Aug
Wed13 Aug
from US$92
Thu14 Aug

Cheap buses leaving Wednesday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 13 August at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: 14 August at
    Destination city: Jacksonville
    Destination location: Jacksonville Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 13 August at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: 13 August at
    Destination city: Jacksonville
    Destination location: Jacksonville Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 13 August at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: 13 August at
    Destination city: Jacksonville
    Destination location: Jacksonville Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 13 August at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: 14 August at
    Destination city: Jacksonville
    Destination location: Jacksonville Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 13 August at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: 14 August at
    Destination city: Jacksonville
    Destination location: Jacksonville Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

Accepted payments

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Compare 2 ways to travel from Greenville to Jacksonville

Bus
Average priceUS$86 - US$180Average duration15h 35m
13kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average priceUS$158 - US$1,199Average duration1d 7h
46kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Greenville to Jacksonville

Among the sustainable travel choices, the bus stands out as a good way to reach Jacksonville. The journey takes about 15 hours 35 minutes and with fares starting at just US$86, it presents an excellent value for a comfortable ride.

3bus per day
15h 35mAverage duration
US$86Cheapest ticket
13kgCO₂ emissions

Bus Greenville, SC to Jacksonville, FL: Trip Overview

Average ticket priceUS$104
Average bus trip duration15h 35m
Number of daily buses3
Earliest bus departure08:40
Distance313 miles
Latest bus departure22:00

Greenville to Jacksonville Bus

Busbud helps you find a bus from Greenville to Jacksonville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Greenville to Jacksonville.

Discover how much the bus trip from Greenville to Jacksonville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Greenville, SC - Jacksonville, FL

  1. How far is Jacksonville from Greenville by coach?

    The distance between Greenville and Jacksonville by coach is approximately 315 miles (508 km).

  2. Is there a way to reach Jacksonville from Greenville without flying?

    You have the option to select the coach for your journey on this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/08
US$86
06/08
No data
Today
US$87
08/08
No data
09/08
No data
10/08
No data
11/08
No data
12/08
No data
busbud logoThe cheapest trip from Greenville, SC to Jacksonville, FL was searched and found on 5 Aug 2025 with a price of US$86

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Jacksonville, FL as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Greenville and Jacksonville!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Greenville to Jacksonville.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Greenville to Jacksonville will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Greenville to Jacksonville.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

What's the cheapest way to go from Greenville, SC to Jacksonville, FL?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Greenville, SC by bus?

Bus from Greenville, SC to Jacksonville, FL

You can also go to Jacksonville, FL by train

Train from Greenville, SC to Jacksonville, FL

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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