Bus Gainesville to San Diego: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Gainesville to San Diego Bus
Busbud helps you find a bus from Gainesville to San Diego. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Gainesville to San Diego.
From cheap bus tickets to more luxurious buses traveling from Gainesville to San Diego, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Frequently asked questions for your trip Gainesville (TX) - San Diego (CA), US
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Gainesville to San Diego was searched and found on Jun 8, 2025 with a price of $223To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Gainesville to San Diego, as early as possible.
You can expect to pay from $223 to $275 for a bus ticket from Gainesville to San Diego based on the last 2 days. You can expect to find the cheapest price for the trip at $223 which is on 2025-06-08.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Gainesville and San Diego!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Gainesville to San Diego.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Gainesville to San Diego that are otherwise impossible to come by with a plane.
Tune out to the fine sounds of your best music playlist on your bus trip from Gainesville to San Diego while indulging in miles on end of beautiful scenic views.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
Top traveled bus routes
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Popular Buses Connecting Gainesville
Buses Leaving from Gainesville
- Bus from Gainesville to Tampa
- Bus Gainesville - Orlando
- Gainesville - Atlanta
- Bus from Gainesville to Midland
- Bus Gainesville - Temple
- Gainesville - Dallas
- Bus from Gainesville to Austin
- Bus Gainesville - Colorado Springs
- Gainesville - Oklahoma City
- Bus from Gainesville to Denver
- Bus Gainesville - Houston
- Gainesville - San Antonio
- Bus from Gainesville to Knoxville
Buses Going to Gainesville
- Bus from Tampa to Gainesville
- Bus Miami - Gainesville
- Miami - Gainesville
- Bus from Orlando to Gainesville
- Bus Fort Lauderdale - Gainesville
- Sarasota - Gainesville
- Bus from Dallas to Gainesville
- Bus Austin - Gainesville
- Denton - Gainesville
- Bus from Houston to Gainesville
- Bus San Antonio - Gainesville
- Monroe - Gainesville
- Bus from Oklahoma City to Gainesville
- Bus Albuquerque - Gainesville
Popular Buses Connecting San Diego
Buses Leaving from San Diego
Buses Going to San Diego
- Bus from Manchester to San Diego
- Bus San Marcos - San Diego
- Santa Fe - San Diego
- Bus from Grants to San Diego
- Bus Spring Hill - San Diego
- Los Angeles - San Diego
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- Bus Las Vegas - San Diego
- Phoenix - San Diego
- Bus from Menifee to San Diego
- Bus El Centro - San Diego
- Yuma - San Diego