What is the distance between Chicago and San Diego?

About 1729 miles (2788 km) separate Chicago and San Diego.

What are the departure and arrival stations when taking the bus from Chicago to San Diego?

If you're headed to San Diego from Chicago, chances are that your bus will leave from Downtown Greyhound Station and arrive at Mission Valley Sheraton. These are the main departure and arrival locations on this route, but you can also find other options that could better fit your plans.

What are the best sights and things to do in San Diego?

Once in San Diego, you can start exploring the city and discover its surroundings. The top sights and things to do are Coronado, The Gaslamp Quarter, San Diego Zoo, Torrey Pines Gliderport and USS Midway Museum.

Bus Chicago to San Diego from $130 | Refundable Tickets

Previously seen trips

Next departures for Chicago to San Diego on November 17
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound + FlixBus	Bus	10:30pm	Downtown Greyhound Station	2d 14h	10:30am	Downtown SD (Seaport)	No tags
FlixBus + Greyhound	Bus	10:30pm	Chicago 95Th & Dan Ryan	2d 18h	2:50pm	San Diego (Old Town-FlixBus)	No tags
Greyhound + FlixBus	Bus	10:30pm	Downtown Greyhound Station	2d 13h	10:10am	Balboa Park	No tags
Greyhound + FlixBus	Bus	10:30pm	Chicago 95Th & Dan Ryan	2d 4h	1:10am	Downtown SD (Seaport)	No tags
FlixBus + Greyhound	Bus	10:30pm	Chicago 95Th & Dan Ryan	2d 17h	2:20pm	UCSD Health La Jolla Station	No tags

Compare 2 ways to go from Chicago to San Diego

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach San Diego. The journey takes about 2 days, 42 minutes and with fares starting at just $186, it presents an excellent value for a comfortable ride.

3train per day

2d Average Duration

1728 milesDistance

254kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$125 - $582	Average Duration2d 7h	CO₂ emissions 69kg CO₂e
Train	Average Price$186 - $1,547	Average Duration2d	CO₂ emissions 254kg CO₂e

Compare bus companies

Greyhound

3.5/587,378 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/511,356 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in Chicago and San Diego?

Stops in Chicago

A - Downtown Greyhound Station

B - Chicago O'Hare International Airport

C - Polk St & Canal St

D - Tornado Bus S Kedzie Ave

E - Cumberland CTA

F - Turimex California Ave

Stops in San Diego

A - Mission Valley Sheraton

B - Old Town Courtyard Marriot

C - Downtown Holiday Inn

D - Greyhound Station

E - Market St. & Park Blvd

F - San Ysidro McDonald's

Frequently asked questions about traveling from Chicago to San Diego, CA, US by bus

What is the distance between Chicago and San Diego?
What are the departure and arrival stations when taking the bus from Chicago to San Diego?
What are the best sights and things to do in San Diego?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/15

No data

11/16

$207

Today

$165

11/18

$132

11/19

No data

11/20

$153

11/21

$171

11/22

$130

The cheapest trip from Chicago to San Diego, CA, US was searched and found on Nov 22, 2025 with a price of $130

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to San Diego, CA, US, as early as possible.

You can expect to pay from $130 to $220 for a bus ticket from Chicago to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $130 which is on 2025-11-22.