Bus Tickets from Chicago to San Antonio, US

Next departures

Next departures for Chicago to San Antonio on October 3
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc. + Valley Transit
Chicago 95Th & Dan Ryan
San Antonio Bus StationCheapest
Tornado Bus + Expreso
Chicago, IL
Tornado I-35Fastest
FlixBus + Greyhound Lines, Inc. + Valley Transit
Downtown Greyhound Station
San Antonio Bus StationNo tags
Greyhound Lines, Inc. + Greyhound Lines Mexico
Downtown Greyhound Station
San Antonio Bus StationNo tags
Greyhound Lines, Inc. + FlixBus
Downtown Greyhound Station
Pearl DistrictNo tags

Last refresh of the prices: Yesterday at 10:45 PM CDT.

Accepted payments

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Compare 2 ways to go from Chicago to San Antonio.

Bus
Average Price$71 - $389Average Duration1d 3h
42kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$121 - $585Average Duration1d 12h
154kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Chicago to San Antonio

Among the sustainable travel choices, the bus stands out as the good way to reach San Antonio. The journey takes about 1 day, 3 hours and with fares starting at just $71, it presents an excellent value for a comfortable ride.

36bus per day
1d 3hAverage Duration
$71Cheapest ticket
42kgCO₂ emissions

Bus Chicago to San Antonio, US: Trip Overview

Average ticket price$148
Average bus trip duration1d 3h
Number of daily buses36
Earliest bus departure12:15am
Distance1052 miles (1696 km)
Latest bus departure11:59pm

Chicago to San Antonio Bus

With Busbud, comparing and booking tickets for a bus from Chicago to San Antonio is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Chicago to San Antonio.

Whether it is cheap bus tickets or more luxurious buses going to San Antonio from Chicago, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Chicago - San Antonio, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/30
$255
10/01
$255
Today
$255
10/03
$255
10/04
$255
10/05
$255
10/06
$255
10/07
$255
busbud logoThe cheapest trip from Chicago to San Antonio, US was searched and found on Sep 30, 2025 with a price of $255

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to San Antonio, US, as early as possible.

You can expect to pay from $255 to $270 for a bus ticket from Chicago to San Antonio, US based on the last 2 days. You can expect to find the cheapest price for the trip at $255 which is on 2025-10-03.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Chicago to San Antonio.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Chicago to San Antonio.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Chicago to San Antonio.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Chicago to San Antonio.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

What's the cheapest way to go from Chicago to San Antonio, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Chicago by bus?

Bus from San Antonio, US to Chicago

You can also go to San Antonio, US by train

Train from Chicago to San Antonio, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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