Bus Tickets from Chicago to Charleston, SC, US

Next departures

Next departures for Chicago to Charleston on October 3
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
537-517 W. Jackson Blvd
4565 Gaynor Ave, North CharlestonCheapest
FlixBus
Chicago 95Th & Dan Ryan
4565 Gaynor Ave, North CharlestonFastest
FlixBus
Downtown Greyhound Station
4565 Gaynor Ave, North CharlestonNo tags
Greyhound Lines, Inc. + FlixBus
537-517 W. Jackson Blvd
4565 Gaynor Ave, North CharlestonNo tags
FlixBus + Greyhound Lines, Inc.
Chicago 95Th & Dan Ryan
4565 Gaynor Ave, North CharlestonNo tags

Last refresh of the prices: Today at 7:21 PM CDT.

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Compare 2 ways to go from Chicago to Charleston.

Bus
Average Price$93 - $274Average Duration1d 2h
30kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$219 - $477Average Duration1d 9h
110kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Chicago to Charleston

Among the sustainable travel choices, the bus stands out as the good way to reach Charleston. The journey takes about 1 day, 2 hours 50 minutes and with fares starting at just $93, it presents an excellent value for a comfortable ride.

5bus per day
1d 2hAverage Duration
$93Cheapest ticket
30kgCO₂ emissions

Bus Chicago to Charleston, SC, US: Trip Overview

Average ticket price$147
Average bus trip duration1d 2h
Number of daily buses5
Earliest bus departure10:00am
Distance748 miles (1206 km)
Latest bus departure11:50pm

Chicago to Charleston Bus

Busbud helps you find a bus from Chicago to Charleston. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Chicago to Charleston.

Whether it is cheap bus tickets or more luxurious buses going to Charleston from Chicago, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Chicago - Charleston, SC, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/29
$91
09/30
$109
Today
$170
10/02
$88
10/03
$148
10/04
No data
10/05
No data
10/06
No data
busbud logoThe cheapest trip from Chicago to Charleston, SC, US was searched and found on Oct 2, 2025 with a price of $88

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Charleston, SC, US, as early as possible.

You can expect to pay from $88 to $256 for a bus ticket from Chicago to Charleston, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $88 which is on 2025-10-02.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Chicago and Charleston!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Chicago to Charleston.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Chicago to Charleston.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Chicago to Charleston.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from Chicago to Charleston, SC, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Chicago by bus?

Bus from Charleston, SC, US to Chicago

You can also go to Charleston, SC, US by train

Train from Chicago to Charleston, SC, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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