Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Terminal de Buses La Serena | Av. Balmaceda | Cheapest | |||||
 | Terminal de Buses La Serena | Terminal de buses Calama | Fastest | |||||
| Terminal de Buses La Serena | Calama | No tags | |||||
| Terminal de Buses La Serena | Av. Balmaceda | No tags | |||||
 | La Serena (Bus terminal La Serena) | Calama (Terminale de buses Granaderos) | No tags |
Last refresh of the prices: Today at 9:13 AM -03.
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Get from La Serena to Calama
This route is served by bus onlyThe journey takes about 15 hours 50 minutes, and with fares starting at just US$29, it presents an excellent value for a comfortable ride.
Bus La Serena, CL to Calama: Trip Overview
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La Serena to Calama Bus
Busbud helps you find a bus from La Serena to Calama. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from La Serena to Calama.
From cheap bus tickets to more luxurious buses travelling from La Serena to Calama, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in La Serena and Calama?
Frequently asked questions on the trip La Serena, CL - Calama
How much does a bus ticket from La Serena to Calama cost?
The bus ticket price from La Serena to Calama starts at US$29. The best way to find cheap bus tickets from La Serena to Calama is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from La Serena to Calama?
The average travel time between La Serena and Calama is around 15h 50m, although the fastest bus will take about 14h 45m. This is the time it takes to travel the 861 km that separates the two cities.
How many daily bus connections are there between La Serena and Calama?
The number of buses from La Serena to Calama can differ depending on the day of the week. On average, there are 18 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from La Serena to Calama by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from La Serena to Calama?
When taking the bus from La Serena to Calama, you can travel comfortably and safely with Pluss Chile, Cikbus Elité, Buses Andimar.
What are the departure and arrival stations when taking the bus from La Serena to Calama?
Buses travelling between La Serena and Calama leave from Terminal de Buses La Serena or Rotonda La Serena and arrive at Av. Balmaceda, Calama, Parada de Autobuses de Calama - Ascotan.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from La Serena, CL to Calama was searched and found on 03 Nov 2025 with a price of US$28To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from La Serena, CL to Calama as early as possible.
You can expect to pay from US$28 to US$55 for a bus ticket from La Serena, CL to Calama based on the last 2 days. You can expect to find the cheapest price for the trip at US$28, which is on 2025-11-03.
Usually Pluss Chile will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between La Serena and Calama!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from La Serena to Calama.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from La Serena to Calama that are otherwise impossible to come by with a plane.
Make a music playlist for your bus ride from La Serena to Calama, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
Top travelled bus routes
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Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
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Popular Buses Connecting La Serena
Buses Leaving from La Serena
- Bus from La Serena to Coquimbo
- Coach La Serena - Santiago
- Bus La Serena - Temuco
- Bus from La Serena to Ovalle
- Coach La Serena - Antofagasta
- Bus La Serena - Vallenar
- Bus from La Serena to Calama
- Coach La Serena - Los Vilos
- Bus La Serena - Quillota
- Bus from La Serena to El Salvador
- Coach La Serena - Puerto Varas
- Bus La Serena - Villarrica
- Bus from La Serena to Linares
- Coach La Serena - Osorno Province
- Bus La Serena - Tongoy
Buses Going to La Serena
- Bus from Santiago to La Serena
- Coach Ovalle - La Serena
- Bus Copiapo - La Serena
- Bus from Calama to La Serena
- Coach Temuco - La Serena
- Bus Valparaiso - La Serena
- Bus from San Antonio to La Serena
- Coach Baquedano - La Serena
- Bus Antofagasta - La Serena
- Bus from Pullalli to La Serena
- Coach Osorno Province - La Serena
- Bus Caldera - La Serena
- Bus from Taltal to La Serena
- Coach Los Vilos - La Serena
- Bus Concon - La Serena
Popular Buses Connecting Calama
Buses Leaving from Calama
- Bus from Calama to Iquique
- Coach Calama - La Serena
- Bus Calama - Antofagasta
- Bus from Calama to Sierra Gorda
- Coach Calama - Copiapo
- Bus Calama - Santiago
- Bus from Calama to Arica Province
- Coach Calama - Quillota
- Bus Calama - Puerto Montt
- Bus from Calama to Pullalli
- Coach Calama - Pucon
- Bus Calama - Alto Hospicio
- Bus from Calama to Vallenar
- Coach Calama - Coquimbo
- Bus Calama - Valdivia
Buses Going to Calama
- Bus from Iquique to Calama
- Coach Copiapo - Calama
- Bus Uyuni - Calama
- Bus from Sierra Gorda to Calama
- Coach Coquimbo - Calama
- Bus Vallenar - Calama
- Bus from La Serena to Calama
- Coach Puerto Montt - Calama
- Bus Quillota - Calama
- Bus from Pullalli to Calama
- Coach Antofagasta - Calama
- Bus Ovalle - Calama
- Bus from Puerto Varas to Calama
- Coach Arica Province - Calama
- Bus Valdivia - Calama