Find coaches from Louisville to Panama City, US

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Bus Louisville to Panama City: Trip Overview

Average ticket priceUS$178
Average bus trip duration20h 20m
Number of daily buses2
Earliest bus departure14:20
Distance556 miles
Latest bus departure18:20

Louisville to Panama City Bus

Busbud helps you find a bus from Louisville to Panama City. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Louisville to Panama City will be provided by the most trusted bus companies.

Discover how much the bus trip from Louisville to Panama City will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Louisville - Panama City, US

  1. How far is Panama City from Louisville by coach?

    The distance between Louisville and Panama City by coach is approximately 559 miles (901 km).

  2. What is the best way to go from Louisville to Panama City without flying?

    You have the option to select the coach for your journey on this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
16/06
US$170
17/06
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busbud logoThe cheapest trip from Louisville to Panama City was searched and found on 16 Jun 2025 with a price of US$170

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Louisville to Panama City as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Louisville and Panama City!

Much more than a mere vehicle taking you from Louisville to Panama City, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Louisville to Panama City will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Make a music playlist for your bus ride from Louisville to Panama City, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Louisville by bus?

Bus from Louisville to Panama City

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