Find coaches from Indianapolis to Panama City, US

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Today6 Jun
Tomorrow7 Jun
Sun8 Jun
Mon9 Jun
Tue10 Jun
Wed11 Jun
Thu12 Jun
from US$129
Fri13 Jun

Cheap buses leaving Thursday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: 12 June at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: 13 June at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 12 June at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: 13 June at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 12 June at
    Departure city: Indianapolis
    Departure location: Downtown Transit Center
    Arrival time: 14 June at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Indianapolis to Panama City: Trip Overview

Average ticket priceUS$148
Average bus trip duration1d 2h
Number of daily buses3
Earliest bus departure11:25
Distance661 miles
Latest bus departure23:30

Indianapolis to Panama City Bus

Busbud helps you find a bus from Indianapolis to Panama City. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Indianapolis to Panama City from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Panama City from Indianapolis, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Indianapolis - Panama City, US

  1. How much is the coach fare from Indianapolis to Panama City?

    The price for a coach ticket from Indianapolis to Panama City starts at US$97, though the average is US$148. The cost of tickets can fluctuate based on factors like the time of day, the company, and the class you choose. Use Busbud to compare prices and amenities offered by different companies, ensuring you find the most favorable deals and promotions.

  2. How long is the coach ride from Indianapolis to Panama City?

    The average duration for a trip from Indianapolis to Panama City by coach is around 1d 2h. If you're looking for the fastest trip, you can get there in just about 22h 50m. Please be aware that the time it takes for your journey may vary depending on the traffic conditions along the route.

  3. At what time is the first coach from Indianapolis to Panama City?

    The first departure to Panama City is at 11:25. Times and services may vary during weekends and holidays.

  4. How far is Panama City from Indianapolis by coach?

    The distance between Indianapolis and Panama City by coach is approximately 664 miles (1071 km).

  5. What is the best way to go from Indianapolis to Panama City without flying?

    You have the option to select the coach for your journey on this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.

  6. Is there am overnight coach from Indianapolis to Panama City?

    You can hop on coaches departing from Indianapolis until 23:30 and reaching Panama City the following day. Remember to bring along some essentials like a snuggly blanket and a few treats for a comfortable trip.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/06
US$132
05/06
US$177
Today
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busbud logoThe cheapest trip from Indianapolis to Panama City was searched and found on 4 Jun 2025 with a price of US$132

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Panama City as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Indianapolis and Panama City!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Indianapolis to Panama City, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Indianapolis to Panama City.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Indianapolis to Panama City.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Indianapolis by bus?

Bus from Indianapolis to Panama City

Why choose Busbud?

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