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- This trip is recommended because it is the: Cheapest + FastestDeparture time: 7 August atDeparture city: LouisvilleDeparture location: Louisville, KYArrival time: 7 August atDestination city: ChicagoDestination location: Chicago 95Th & Dan RyanOperated by: FlixBus
Vehicle: BusDuration: - Departure time: 7 August atDeparture city: LouisvilleDeparture location: Louisville, KYArrival time: 7 August atDestination city: ChicagoDestination location: Downtown Greyhound StationOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration: - Departure time: 7 August atDeparture city: LouisvilleDeparture location: Louisville, KYArrival time: 8 August atDestination city: ChicagoDestination location: Downtown Greyhound StationOperated by: FlixBusVehicle: BusDuration:
- Departure time: 7 August atDeparture city: LouisvilleDeparture location: Louisville, KYArrival time: 7 August atDestination city: ChicagoDestination location: Chicago 95Th & Dan RyanOperated by: Greyhound Lines, Inc.Vehicle: BusDuration:
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Bus Louisville to Chicago: Trip Overview
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Louisville to Chicago Bus
With Busbud, comparing and booking tickets for a bus from Louisville to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make it our job to connect you with the most dependable bus companies that cover bus service from Louisville to Chicago.
Whether it is cheap bus tickets or more luxurious buses going to Chicago from Louisville, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Louisville and Chicago?
Frequently asked questions on the trip Louisville - Chicago
How far is Chicago from Louisville by coach?
The distance between Louisville and Chicago by coach is approximately 268 miles (432 km).
Is there a way to reach Chicago from Louisville without flying?
You have the option to select the coach for your journey on this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You also have the option of utilising carpooling services.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Louisville to Chicago was searched and found on 12 Aug 2025 with a price of US$42To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Louisville to Chicago as early as possible.
You can expect to pay from US$42 to US$103 for a bus ticket from Louisville to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at US$42, which is on 2025-08-12.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Louisville to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Louisville to Chicago.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Louisville to Chicago.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Louisville to Chicago.
Did you know?
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
Top travelled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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