Find coaches from La Serena, CL to Mendoza, AR

Find affordable coach tickets from La Serena, CL to Mendoza, AR with flexible options. Book your journey now

Join 75M+ travellers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every stage.
Cancel anytime and receive a 100% refund, no reason needed.
Tomorrow10 Aug
from US$60
Mon11 Aug
from US$58
Tue12 Aug
from US$58
Wed13 Aug
from US$58
Thu14 Aug
from US$62
Fri15 Aug
from US$62
Sat16 Aug
Sun17 Aug

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 10 August at
    Departure city: La Serena
    Departure location: Terminal de Buses La Serena
    Arrival time: 10 August at
    Destination city: Mendoza
    Destination location: Mendoza Terminal
    Operated by: Cikbus Elité + Andesmar
    Cikbus Elité + Andesmar
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 10 August at
    Departure city: La Serena
    Departure location: Terminal de Buses La Serena
    Arrival time: 10 August at
    Destination city: Mendoza
    Destination location: Terminal De Omnibus Guaymallen
    Operated by: CATA InternacionalCATA Internacional
    Vehicle: BusDuration:
  • Departure time: 10 August at
    Departure city: La Serena
    Departure location: Terminal de Buses La Serena
    Arrival time: 10 August at
    Destination city: Mendoza
    Destination location: Terminal De Omnibus Guaymallen
    Operated by: CATA InternacionalCATA Internacional
    Vehicle: BusDuration:
  • Departure time: 10 August at
    Departure city: La Serena
    Departure location: Terminal de Buses La Serena
    Arrival time: 11 August at
    Destination city: Mendoza
    Destination location: Mendoza Terminal
    Operated by: Cikbus Elité + Andesmar
    Cikbus Elité + Andesmar
    Vehicle: BusDuration:
  • Departure time: 10 August at
    Departure city: La Serena
    Departure location: Terminal de Buses La Serena
    Arrival time: 11 August at
    Destination city: Mendoza
    Destination location: Terminal De Omnibus Guaymallen
    Operated by: Cikbus Elité + CATA Internacional
    Cikbus Elité + CATA Internacional
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus La Serena, CL to Mendoza, AR: Trip Overview

Average ticket priceUS$61
Average bus trip duration15h 45m
Number of daily buses4
Earliest bus departure05:10
Distance251 miles
Latest bus departure23:59

La Serena to Mendoza Bus

With Busbud, comparing and booking tickets for a bus from La Serena to Mendoza is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from La Serena to Mendoza.

Whether it is cheap bus tickets or more luxurious buses going to Mendoza from La Serena, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip La Serena, CL - Mendoza, AR

  1. How far is Mendoza from La Serena by coach?

    The journey from La Serena to Mendoza by coach covers an approximate distance of 251 miles (405 km).

  2. Is there a way to reach Mendoza from La Serena without flying?

    You can choose the coach to travel this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/08
No data
08/08
No data
Today
No data
10/08
US$70
11/08
No data
12/08
No data
13/08
No data
14/08
No data
busbud logoThe cheapest trip from La Serena, CL to Mendoza, AR was searched and found on 10 Aug 2025 with a price of US$70

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from La Serena, CL to Mendoza, AR as early as possible.

You can expect to pay from US$70 to US$82 for a bus ticket from La Serena, CL to Mendoza, AR based on the last 2 days. You can expect to find the cheapest price for the trip at US$70, which is on 2025-08-10.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from La Serena to Mendoza.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from La Serena to Mendoza.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from La Serena to Mendoza.

Make a music playlist for your bus ride from La Serena to Mendoza, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to La Serena, CL by bus?

Bus from La Serena, CL to Mendoza, AR

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting La Serena

Buses Leaving from La Serena

Buses Going to La Serena

Popular Buses Connecting Mendoza

Buses Leaving from Mendoza

Buses Going to Mendoza