Bus Tickets from La Serena, CL to Mendoza, AR

Next departures

Next departures for La Serena to Mendoza on October 1
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Cikbus Elité + Chi-ar Internacional
Terminal de Buses La Serena
Terminal Omnibus del Sol (Mendoza)CheapestFastest
Cikbus Elité + Chi-ar Internacional
Terminal de Buses La Serena
Terminal Omnibus del Sol (Mendoza)No tags
Cikbus Elité + Chi-ar Internacional
Terminal de Buses La Serena
Terminal Omnibus del Sol (Mendoza)No tags
Cikbus Elité + Chi-ar Internacional
Terminal de Buses La Serena
Terminal Omnibus del Sol (Mendoza)No tags

Last refresh of the prices: Today at 1:04 AM -03.

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Bus La Serena, CL to Mendoza, AR: Trip Overview

Average Ticket PriceUS$69
Average Bus Trip Duration17h 25m
Number of daily buses5
Earliest bus departure1:10am
Distance404 km
Latest bus departure11:59pm

La Serena to Mendoza Bus

With Busbud, comparing and booking tickets for a bus from La Serena to Mendoza is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from La Serena to Mendoza.

Whether it is cheap bus tickets or more luxurious buses going to Mendoza from La Serena, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip La Serena, CL - Mendoza, AR

  1. What is the travel distance from La Serena to Mendoza?

    It's about 405 km (251 miles) from La Serena to Mendoza.

  2. What are the departure and arrival locations for buses traveling from La Serena to Mendoza?

    Buses departing from Terminal de Buses La Serena in La Serena will take you to Mendoza Terminal in Mendoza.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09-28
US$70
09-29
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Today
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10-01
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10-02
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busbud logoThe cheapest trip from La Serena, CL to Mendoza, AR was searched and found on Sep 28, 2025 with a price of US$70

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from La Serena, CL to Mendoza, AR, as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from La Serena to Mendoza.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from La Serena to Mendoza.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from La Serena to Mendoza.

Make a music playlist for your bus ride from La Serena to Mendoza, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to La Serena, CL by bus?

Bus from Mendoza, AR to La Serena, CL

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