Bus Tupelo to Panama City: Trip Overview
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Based on 87034 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at US$83.00
Tupelo to Panama City Bus
Busbud helps you find a bus from Tupelo to Panama City. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Tupelo to Panama City.
Discover how much the bus trip from Tupelo to Panama City will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Frequently asked questions on the trip Tupelo - Panama City, US
How long is the bus ride from Tupelo to Panama City?
The typical travel time from Tupelo to Panama City by bus is around 14h 25m. For the shortest travel time, select the fastest bus available, which will take you to Panama City in about 14h 25m.
How far is Tupelo from Panama City?
The distance between Tupelo and Panama City is approximately 535 km (332 miles).
What is the cheapest way to get from Tupelo to Panama City?
The least expensive way to go from Tupelo to Panama City would be going by bus. The ticket price for this bus starts at US$83, making this your best choice for this trip.
How much does it cost to take the bus from Tupelo to Panama City?
You can expect to pay around US$83 for the bus ride from Tupelo to Panama City.
Can I take an overnight bus from Tupelo to Panama City?
Yes! If you're heading from Tupelo to Panama City, you'll find buses departing until 11:15pm and arriving the next day.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tupelo to Panama City was searched and found on Jun 13, 2025 with a price of US$154To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tupelo to Panama City, as early as possible.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Tupelo and Panama City!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Tupelo to Panama City.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Tupelo to Panama City will emit less CO2 than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Tupelo to Panama City.
Did you know?
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
Top travelled bus routes
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Popular Buses Connecting Tupelo
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Buses Going to Tupelo
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Popular Buses Connecting Panama City
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Buses Going to Panama City
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