Bus Tickets from San Antonio (TX), US to Panama City, US

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Bus San Antonio to Panama City: Trip Overview

Average Ticket PriceUS$120
Average Bus Trip Duration23h 5m
Number of daily buses1
Earliest bus departure7:45am
Distance1228 km
Latest bus departure4:45pm

San Antonio to Panama City Bus

With Busbud, comparing and booking tickets for a bus from San Antonio to Panama City is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from San Antonio to Panama City.

Discover how much the bus trip from San Antonio to Panama City will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip San Antonio (TX), US - Panama City, US

  1. How long is the trip from San Antonio to Panama City by bus?

    The typical travel time from San Antonio to Panama City by bus is around 23h 5m. The fastest bus on this trip will get to Panama City in 19h 50m

  2. What is the travel distance from San Antonio to Panama City?

    The distance covered from San Antonio to Panama City is 1241 km (770 miles).

  3. What are the departure and arrival locations for buses traveling from San Antonio to Panama City?

    Buses traveling this route start their trip at San Antonio Bus Station, in San Antonio, and end it at Panama City Greyhound Bus Station, in Panama City.

  4. What is the cheapest way to go from San Antonio to Panama City?

    Taking the bus is the cheapest option to travel from San Antonio to Panama City. Starting at US$102, this bus is the most cost-effective option for your journey.

  5. How much does the bus ticket cost from San Antonio to Panama City?

    The bus fare from San Antonio to Panama City is approximately US$120.

  6. Is there an overnight bus from San Antonio to Panama City?

    Yes! Catch buses leaving from San Antonio until 4:45pm and reaching Panama City on the following day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-23
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05-28
US$130
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busbud logoThe cheapest trip from San Antonio to Panama City was searched and found on May 28, 2025 with a price of US$130

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio to Panama City, as early as possible.

You can expect to pay from US$130 to US$130 for a bus ticket from San Antonio to Panama City based on the last 2 days. You can expect to find the cheapest price for the trip at US$130 which is on 2025-05-28.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from San Antonio to Panama City.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from San Antonio to Panama City.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from San Antonio to Panama City will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from San Antonio to Panama City.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to San Antonio by bus?

Bus from San Antonio to Panama City

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