Compare 2 ways to go from Portland to Greenville
Busbud recommends taking the bus from Portland to GreenvilleAmong the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 3 days, 2 hours 30 minutes, and with fares starting at just US$230, it presents an excellent value for a comfortable ride.
Bus Portland, OR to Greenville, SC: Trip Overview
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Portland to Greenville Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Portland to Greenville.
Bus service from Portland to Greenville will be provided by the most trusted bus companies.
From cheap bus tickets to more luxurious buses travelling from Portland to Greenville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Portland and Greenville?
Frequently asked questions on the trip Portland, OR - Greenville, SC
What is the travel distance from Portland to Greenville?
The distance between Portland and Greenville is around 3583 km (2222 miles).
What are the departure and arrival locations for buses traveling from Portland to Greenville?
Buses traveling this route start their trip at Portland Union Station, in Portland, and end it at Guadalajara Supermarket Bus Stop, in Greenville.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Portland, OR to Greenville, SC was searched and found on Aug 4, 2025 with a price of US$348To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Portland, OR to Greenville, SC, as early as possible.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Portland to Greenville but it'll also be endearing to native speakers who will surely appreciate your effort.
Much more than a mere vehicle taking you from Portland to Greenville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Portland to Greenville that are otherwise impossible to come by with a plane.
Make a music playlist for your bus ride from Portland to Greenville, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
What's the cheapest way to go from Portland, OR to Greenville, SC?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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Popular Buses Connecting Portland
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Buses Going to Greenville
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