Bus Tickets from Penco to Santiago, CL

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TodayMay 29
from US$14
TomorrowMay 30
SatMay 31
SunJun 1
MonJun 2
TueJun 3
WedJun 4
ThuJun 5

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: May 29 at
    Departure city: Penco
    Departure location: Penco
    Arrival time: May 29 at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: May 29 at
    Departure city: Penco
    Departure location: Penco
    Arrival time: May 30 at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:
  • Departure time: May 29 at
    Departure city: Penco
    Departure location: Penco
    Arrival time: May 30 at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:
  • Departure time: May 29 at
    Departure city: Penco
    Departure location: Penco
    Arrival time: May 30 at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:
  • Departure time: May 29 at
    Departure city: Penco
    Departure location: Penco
    Arrival time: May 29 at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:

Last refresh of the prices: 2025-05-22 -04.

Prices and availability are subject to change.

Accepted payments

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Bus Penco to Santiago: Trip Overview

Average Ticket PriceUS$20
Average Bus Trip Duration5h 6m
Number of daily buses9
Earliest bus departure12:19am
Distance420 km
Latest bus departure11:55pm

Penco to Santiago Bus

With Busbud, comparing and booking tickets for a bus from Penco to Santiago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Penco to Santiago.

Whether it is cheap bus tickets or more luxurious buses going to Santiago from Penco, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Penco - Santiago, CL

  1. How long is the bus ride from Penco to Santiago?

    The trip from Penco to Santiago will take on average 5h 6m. The fastest bus on this trip will get to Santiago in 5h 6m

  2. How far is Penco from Santiago?

    The distance between Penco and Santiago is approximately 429 km (266 miles).

  3. What are the departure and arrival locations for buses traveling from Penco to Santiago?

    Buses departing from Terminal de Autobuses de Penco in Penco will take you to Terminal Sur in Santiago.

  4. What is the cheapest way to get from Penco to Santiago?

    If you're on a budget, consider traveling by bus to Santiago from Penco; it tends to be more affordable. The ticket price for this bus starts at US$15, making this your best choice for this trip.

  5. How much does it cost to take the bus from Penco to Santiago?

    You can expect to pay around US$20 for the bus ride from Penco to Santiago.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-27
US$13
05-28
US$13
Today
US$13
05-30
No data
05-31
US$14
06-01
No data
06-02
No data
06-03
US$13
busbud logoThe cheapest trip from Penco to Santiago was searched and found on May 28, 2025 with a price of US$13

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Penco to Santiago, as early as possible.

You can expect to pay from US$13 to US$26 for a bus ticket from Penco to Santiago based on the last 2 days. You can expect to find the cheapest price for the trip at US$13 which is on 2025-06-03.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Penco to Santiago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Penco to Santiago.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Penco to Santiago.

Make a music playlist for your bus ride from Penco to Santiago, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Penco by bus?

Bus from Penco to Santiago

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