Bus Tickets from Calama to La Serena, CL

Find affordable bus tickets from Calama to La Serena, CL with flexible options. Book your trip now

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TodayAug 9
from US$39
TomorrowAug 10
from US$33
MonAug 11
from US$29
TueAug 12
from US$33
WedAug 13
from US$33
ThuAug 14
from US$28
FriAug 15
from US$28
SatAug 16
from US$29

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: August 10 at
    Departure city: Calama
    Departure location: Av. Balmaceda
    Arrival time: August 11 at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: Pluss ChilePluss Chile
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: August 10 at
    Departure city: Calama
    Departure location: Calama
    Arrival time: August 11 at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: AndimarAndimar
    Vehicle: BusDuration:
  • Departure time: August 10 at
    Departure city: Calama
    Departure location: Av. Balmaceda
    Arrival time: August 11 at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: Pluss ChilePluss Chile
    Vehicle: BusDuration:
  • Departure time: August 10 at
    Departure city: Calama
    Departure location: Calama
    Arrival time: August 11 at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: AndimarAndimar
    Vehicle: BusDuration:
  • Departure time: August 10 at
    Departure city: Calama
    Departure location: Av. Balmaceda
    Arrival time: August 11 at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: Pluss ChilePluss Chile
    Vehicle: BusDuration:

Last refresh of the prices: Today at 9:21 AM -04.

Prices and availability are subject to change.

Accepted payments

  • Visa
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  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Frequently asked questions on the trip Calama - La Serena, CL

  1. What is the distance between Calama and La Serena?

    The distance between Calama and La Serena is around 861 km (534 miles).

  2. What are the departure and arrival locations for buses traveling from Calama to La Serena?

    Buses traveling this route start their trip at Av. Balmaceda, in Calama, and end it at Terminal de Buses La Serena, in La Serena.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-07
US$36
08-08
US$37
Today
US$31
08-10
US$31
08-11
US$27
08-12
US$31
08-13
US$31
08-14
US$26
busbud logoThe cheapest trip from Calama to La Serena, CL was searched and found on Aug 14, 2025 with a price of US$26

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Calama to La Serena, CL, as early as possible.

You can expect to pay from US$26 to US$61 for a bus ticket from Calama to La Serena, CL based on the last 2 days. You can expect to find the cheapest price for the trip at US$26 which is on 2025-08-14.

Usually PlussChile, Buses Andimar will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Calama to La Serena.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Calama to La Serena, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Calama to La Serena that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Calama to La Serena, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Calama by bus?

Bus from Calama to La Serena, CL

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