Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Calama (Terminale de buses Granaderos) | La Serena (Bus terminal La Serena) | Cheapest | ||||
 | Bus | Terminal de buses Calama | Terminal de Buses La Serena | Fastest | ||||
 | Bus | Av. Balmaceda | Terminal de Buses La Serena | No tags | ||||
| Bus | Calama | Terminal de Buses La Serena | No tags | ||||
| Bus | Calama (Terminale de buses Granaderos) | La Serena (Bus terminal La Serena) | No tags |
Last refresh of the prices: Yesterday at 1:24 PM -04.
Get from Calama to La Serena
The journey takes about 14 hours 5 minutes, and with fares starting at just $42, it presents an excellent value for a comfortable ride.
Where are the popular stops in Calama and La Serena?
Stops in Calama
- AAv. Balmaceda 1940, Calama, Región de Antofagasta, Chile
- B
Calama
Antofagasta 2046, Calama, El Loa 1390714, Antofagasta, Chile - C
Parada de Autobuses de Calama - Ascotan
Ascotán 1891, Calama, Región de Antofagasta, Chile - D
Parada de Autobuses de Calama - Cebollar
Cebollar 1864, Calama, Región de Antofagasta, Chile - E
Terminal: Sub Agencia Avda. Balmaceda
Terminal: Sub Agencia Avda. Balmaceda, Calle O'Higgins O 681, Villa - Caspana, Calama, Antofagasta, Chile - F
Terminal Pullman Bus de Calama
Av. Balmaceda 1802, Calama, Región de Antofagasta, Chile
Stops in La Serena
- AAmunátegui 107, La Serena, Región de Coquimbo, Chile
- B
Rotonda La Serena
Panamericana Norte 208, La Serena, Región de Coquimbo, Chile
Compare bus companies
Frequently asked questions about travelling from Calama to La Serena, CL by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Calama to La Serena?
The cheapest bus tickets from Calama to La Serena start from $42. The average price for this route is around $60. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Calama to La Serena?
The average bus travel time from Calama to La Serena is 14h 5m, covering a distance of 862 km. The quickest bus can get you there in 11h 50m and is operated by Cikbus Elité.
Which bus companies service the Calama to La Serena route?
Several major bus companies operate on this route with 20 buses available per day, including services from Pluss Chile, Cikbus Elité, Buses Andimar, Pullman San Andres, Clikbus.
What are the earliest and latest departure times for the bus from Calama to La Serena?
The earliest bus departs from Calama to La Serena at 8:30am. And the latest bus departs at 10:50pm.
What are the CO₂ emissions for the bus trip from Calama to La Serena?
A bus trip from Calama to La Serena generates an estimated 22 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Calama to La Serena?
According to Busbud customers, the highest-rated bus company on this route is Clikbus, with an average rating of 4.3 out of 5 stars based on 3 reviews.
Which bus company has the best Wi-Fi from Calama to La Serena?
Based on Busbud reviews, the bus company Pluss Chile has the highest Wi-Fi rating with a score of 1.6.
Which bus company has the best on-time performance from Calama to La Serena?
According to Busbud traveller reviews, the most punctual bus company on this route is Clikbus, with a punctuality rating of 5.0 out of 5 stars.
Which bus company has the cleanest buses from Calama to La Serena?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Pluss Chile, with a cleanliness rating of 4.6 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Calama to La Serena, CL was searched and found on Dec 3, 2025 with a price of $40To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Calama to La Serena, CL, as early as possible.
You can expect to pay from $40 to $90 for a bus ticket from Calama to La Serena, CL based on the last 2 days. You can expect to find the cheapest price for the trip at $40 which is on 2025-12-03.
Usually Pluss Chile will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
