Bus Tickets from Greenville (SC) to Detroit (MI)

Find affordable bus tickets from Greenville (SC) to Detroit (MI) with flexible options. Book your trip now

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TodayJun 5
from US$125
TomorrowJun 6
from US$114
SatJun 7
SunJun 8
MonJun 9
TueJun 10
WedJun 11
ThuJun 12

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: June 6 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: June 7 at
    Destination city: Detroit
    Destination location: Detroit Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: June 6 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: June 7 at
    Destination city: Detroit
    Destination location: Detroit Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 6 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: June 7 at
    Destination city: Detroit
    Destination location: Detroit Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Last Sunday at 12:08 PM EDT.

Prices and availability are subject to change.

Accepted payments

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Compare 2 ways to go from Greenville to Detroit

Average PriceUS$77 - US$222Average Duration19h 45m
21kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Average PriceUS$529 - US$558Average Duration1d 18h
76kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Greenville to Detroit

Among the sustainable travel choices, the bus stands out as a good way to reach Detroit. The journey takes about 19 hours 45 minutes, and with fares starting at just US$77, it presents an excellent value for a comfortable ride.

2bus per day
19h 45mAverage Duration
US$77Cheapest ticket
21kgCO₂ emissions

Bus Greenville to Detroit: Trip Overview

Average Ticket PriceUS$126
Average Bus Trip Duration19h 45m
Number of daily buses2
Earliest bus departure1:20pm
Distance836 km
Latest bus departure10:00pm

Greenville to Detroit Bus

With Busbud, comparing and booking tickets for a bus from Greenville to Detroit is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Greenville to Detroit will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Greenville to Detroit, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Greenville (SC) - Detroit (MI)

  1. How long does it take to get to Detroit from Greenville by bus?

    The typical travel time from Greenville to Detroit by bus is around 19h 45m. For the shortest travel time, select the fastest bus available, which will take you to Detroit in about 19h 10m.

  2. What is the distance between Greenville and Detroit?

    The distance covered from Greenville to Detroit is 835 km (518 miles).

  3. What are the departure and arrival locations for buses traveling from Greenville to Detroit?

    Buses traveling this route start their trip at Guadalajara Supermarket Bus Stop, in Greenville, and end it at Detroit Bus Station, in Detroit.

  4. What is the cheapest way to go from Greenville to Detroit?

    The least expensive option to go from Greenville to Detroit would be going by bus. Starting at US$77, this bus is the most cost-effective option for your journey.

  5. How much is the bus from Greenville to Detroit?

    The bus fare from Greenville to Detroit is approximately US$126.

  6. Is it possible to travel by overnight bus from Greenville to Detroit?

    Yes! Catch buses leaving from Greenville until 10:00pm and reaching Detroit on the following day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-03
US$171
06-04
No data
Today
No data
06-06
US$108
06-07
No data
06-08
No data
06-09
No data
06-10
No data
busbud logoThe cheapest trip from Greenville to Detroit was searched and found on Jun 6, 2025 with a price of US$108

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville to Detroit, as early as possible.

You can expect to pay from US$108 to US$171 for a bus ticket from Greenville to Detroit based on the last 2 days. You can expect to find the cheapest price for the trip at US$108 which is on 2025-06-06.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Greenville to Detroit.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Greenville to Detroit, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Greenville to Detroit that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Greenville to Detroit.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

What's the cheapest way to go from Greenville to Detroit?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Greenville by bus?

Bus from Greenville to Detroit

You can also go to Detroit by train

Train from Greenville to Detroit

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