Bus Tickets from Fort Myers to Charleston (SC), US

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Bus Fort Myers to Charleston: Trip Overview

Average Ticket PriceUS$158
Average Bus Trip Duration21h 15m
Number of daily buses1
Earliest bus departure4:35pm
Distance721 km

Fort Myers to Charleston Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Fort Myers to Charleston.

We make sure you can find a bus service from Fort Myers to Charleston from the most reliable bus companies operating this trip.

Discover how much the bus trip from Fort Myers to Charleston will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Fort Myers - Charleston (SC), US

  1. What is the travel distance from Fort Myers to Charleston?

    The distance between Fort Myers and Charleston is approximately 711 km (441 miles).

  2. What are the departure and arrival locations for buses traveling from Fort Myers to Charleston?

    Buses departing from Daniels Pkwy & I-75 in Fort Myers will take you to Charleston Bus Station in Charleston.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-16
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06-17
US$150
Today
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busbud logoThe cheapest trip from Fort Myers to Charleston was searched and found on Jun 17, 2025 with a price of US$150

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Fort Myers to Charleston, as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Fort Myers to Charleston but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Fort Myers to Charleston, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Fort Myers to Charleston will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Fort Myers to Charleston while indulging in miles on end of beautiful scenic views.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Fort Myers by bus?

Bus from Fort Myers to Charleston

You can also go to Charleston by train

Train from Fort Myers to Charleston

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